减重手术后的抗阻训练和蛋白质补充增加力量：一项随机对照试验。

Resistance Training and Protein Supplementation Increase Strength After Bariatric Surgery: A Randomized Controlled Trial.

机构信息

Department of Nutrition, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne Université, Institute of Cardiometabolism and Nutrition (ICAN), Paris, France.

Laboratory of Bioengineering, Tissues and Neuroplasticity (BIOTN), University Paris-Est, Créteil, France.

出版信息

Obesity (Silver Spring). 2018 Nov;26(11):1709-1720. doi: 10.1002/oby.22317.

DOI:10.1002/oby.22317

PMID:30358153

Abstract

OBJECTIVE

Physical activity and dietary regimens to optimize health outcomes after bariatric surgery are not well known. This study aimed to determine whether resistance training with dietary protein supplementation is effective in maintaining body composition and physical fitness after obesity surgery.

METHODS

Seventy-six women with obesity undergoing Roux-en-Y gastric bypass were randomly assigned at the time of surgery to receive either usual care (controls [CON], n = 22), usual care and additional (whey) protein intake (PRO, n = 31), or usual care, additional protein intake, and supervised strength training for 18 weeks (PRO+EX, n = 23). The primary outcome was pre- to 6-month postsurgery change in lean body mass (by dual-energy x-ray absorptiometry). Secondary outcomes included changes in muscle strength (by one-repetition maximum testing).

RESULTS

Loss over time in lean body mass did not differ between groups (CON: mean,-8.8 kg; 95% CI: -10.1 to -7.5 kg; PRO: mean, -8.2 kg; 95% CI: -9.3 to -7.1 kg; PRO+EX: mean, -7.7 kg; 95% CI: -9.0 to -6.5 kg; P = 0.899). The increase in relative lower-limb muscle strength was higher in the PRO+EX group (+0.6 [0.3 to 0.8]) versus +0.1 (-0.1 to 0.4) and +0.2 (0.0 to 0.4) kg/kg body mass in CON and PRO groups, respectively (P = 0.021).

CONCLUSIONS

Loss in muscle strength observed after bariatric surgery can be overcome by resistance training with additional protein intake.

摘要

目的

优化减重手术后的健康结果所需的体力活动和饮食方案并不为人所知。本研究旨在确定阻力训练加膳食蛋白质补充是否能有效维持肥胖手术后的身体成分和身体适应性。

方法

76 名接受 Roux-en-Y 胃旁路术的肥胖女性在手术时被随机分配，分别接受常规护理（对照组[CON]，n = 22）、常规护理和额外（乳清）蛋白质摄入（PRO，n = 31）或常规护理、额外蛋白质摄入和 18 周监督力量训练（PRO+EX，n = 23）。主要结果是手术前至 6 个月手术后瘦体重（通过双能 X 射线吸收法）的变化。次要结果包括肌肉力量的变化（通过一次重复最大测试）。

结果

各组间瘦体重随时间的损失没有差异（CON：平均-8.8 公斤；95%置信区间：-10.1 至-7.5 公斤；PRO：平均-8.2 公斤；95%置信区间：-9.3 至-7.1 公斤；PRO+EX：平均-7.7 公斤；95%置信区间：-9.0 至-6.5 公斤；P = 0.899）。PRO+EX 组的下肢相对肌肉力量增加更高（+0.6 [0.3 至 0.8]），而 CON 和 PRO 组分别增加了+0.1（-0.1 至 0.4）和+0.2（0.0 至 0.4）公斤/公斤体重（P = 0.021）。