Wang Yuan-Yuan, Xiao Le, Rao Wen-Wang, Chai Jing-Xin, Zhang Shu-Fang, Ng Chee H, Ungvari Gabor S, Zhu Huiping, Xiang Yu-Tao
Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Macao SAR, China; Faculty of Health and Life Sciences, De Montfort University, Leicester, United Kingdom.
The National Clinical Research Center for Mental Disorders, China & Center of Depression, Beijing Institute for Brain Disorders & Mood Disorders Center, Beijing Anding Hospital, Capital Medical University, Beijing, China.
J Affect Disord. 2019 Feb 1;244:209-216. doi: 10.1016/j.jad.2018.09.066. Epub 2018 Sep 18.
Depressive symptoms are common in 'left-behind children (LBC)' in China, but their prevalence estimates have been inconsistent. This comprehensive meta-analysis examined the pooled prevalence of depressive symptoms in LBC in China and its associated factors.
Two investigators systematically and independently searched both English (PubMed, PsycINFO, and EMBASE) and Chinese (WanFang Database, CNKI, and SinoMed) databases. Comparative and epidemiological studies reporting the prevalence of depressive symptoms and associated relevant information were included. The prevalence of depressive symptoms was pooled using the random-effects model.
A total of 39 studies covering 31,663 LBC and 20,049 non-LBC controls were included in the meta-analysis. The figures of pooled prevalence of depressive symptoms in LBC and non-LBC were 30.7% and 22.8%, respectively. Subgroup analyses revealed that the use of different scales was significantly associated with the prevalence of depressive symptoms. Compared with non-LBC, LBC were more likely to suffer from depressive symptoms (OR = 1.7, 95% CI: 1.4-1.9).
This meta-analysis confirmed that the prevalence of depressive symptoms in LBC is common in China. In order to reduce the risk of depressive symptoms in this vulnerable segment of the population, the development of screening and therapeutic interventions is urgently needed.
在中国，抑郁症状在留守儿童中很常见，但对其患病率的估计并不一致。这项综合性荟萃分析研究了中国留守儿童抑郁症状的合并患病率及其相关因素。
两名研究人员系统且独立地检索了英文数据库（PubMed、PsycINFO和EMBASE）和中文数据库（万方数据库、中国知网和中国生物医学文献数据库）。纳入报告抑郁症状患病率及相关信息的比较研究和流行病学研究。采用随机效应模型汇总抑郁症状的患病率。
荟萃分析共纳入39项研究，涉及31663名留守儿童和20049名非留守儿童对照。留守儿童和非留守儿童抑郁症状的合并患病率分别为30.7%和22.8%。亚组分析显示，使用不同量表与抑郁症状的患病率显著相关。与非留守儿童相比，留守儿童更易出现抑郁症状（比值比=1.7，95%置信区间：1.4-1.9）。
这项荟萃分析证实，中国留守儿童抑郁症状的患病率较高。为降低这一弱势群体出现抑郁症状的风险，迫切需要开展筛查和治疗干预措施。
