Department of Ophthalmology and Visual Sciences, Osaka City University Graduate School of Medicine, Osaka, Japan.
Acta Ophthalmol. 2010 Aug;88(5):506-13. doi: 10.1111/j.1755-3768.2009.01592.x. Epub 2009 Jul 21.
Our review aims to provide an update of management protocols for congenital nasolacrimal duct obstruction (CNDO). Although early probing performed before the age of 1 year was traditionally recommended, many reports have since confirmed high frequencies of spontaneous resolution during the first year of life. Accordingly, a 'wait-and-see' approach, combined with conservative therapies, is judged to be the best option in infants aged<1 year. By contrast, persistent obstruction beyond 1 year of age warrants probing as a first-line interventional therapy. However, the optimal timing for probing remains controversial. Although there remains a high possibility of spontaneous resolution after the first year of age, this must be balanced against the decrease in success rates for probing that accompanies advancing age. If conservative management fails, persistent CNDO beyond 1 year of age should be managed either by further observation or by primary probing according to the severity of symptoms. In patients in whom probing fails, advanced treatment such as balloon catheter dilation, silicone tube intubation or dacryocystorhinostomy may be considered.
我们的综述旨在提供先天性鼻泪管阻塞(CNDO)管理方案的更新。尽管传统上推荐在 1 岁之前进行早期探通术,但此后许多报道证实,在生命的第一年,自发性缓解的频率很高。因此,对于<1 岁的婴儿,“观察等待”联合保守治疗被认为是最佳选择。相比之下,1 岁以后持续阻塞需要探通术作为一线介入治疗。然而,探通术的最佳时机仍存在争议。虽然在 1 岁以后仍有很高的自发性缓解可能,但这必须与随年龄增长而降低的探通成功率相平衡。如果保守治疗失败,对于 1 岁以后持续存在的 CNDO,应根据症状的严重程度,进一步观察或进行初次探通术。如果探通术失败,可考虑采用球囊导管扩张、硅胶管插管或泪囊鼻腔吻合术等高级治疗方法。