Tinnemans J G, Wobbes T, Hendriks J H, van der Sluis R F, Lubbers E J, de Boer H H
Arch Surg. 1987 Jul;122(7):802-6. doi: 10.1001/archsurg.1987.01400190068013.
Three methods of excising nonpalpable breast lesions have been evaluated: (1) "blind" method, using mammographic coordinates; (2) preoperative localization with the Frank needle; and (3) Frank needle localization aided by a multiperforated compression plate. Successful removal at first attempt occurred in about 80% with any method. The size of the biopsy specimens did not differ significantly among the three groups and is most probably a function of the breast volume. The failure rate was seven (2.1%) of 332 biopsies. Since three of the six repeated biopsies yielded specimens with malignancy, the persistence of a radiographically suspicious lesion on follow-up mammogram of the operated-on breast is an urgent indication for reoperation.
(1) 使用乳腺X线摄影坐标的“盲目”方法；(2) 使用弗兰克针进行术前定位；(3) 借助多孔压迫板的弗兰克针定位。任何一种方法首次尝试成功切除的几率约为80%。三组活检标本的大小无显著差异，很可能是乳腺体积的函数。332例活检中有7例（2.1%）失败。由于6例重复活检中有3例获得了恶性病变的标本，因此，手术侧乳腺随访乳腺X线摄影中出现影像学可疑病变持续存在是再次手术的紧急指征。
