Department of Laboratory Medicine, Kochi Medical School, Kochi University, Kochi, Japan.
Department of Cardiology, Neurology, and Aging Science, Kochi Medical School, Kochi University, Kochi, Japan.
Am J Cardiol. 2018 Dec 15;122(12):2147-2150. doi: 10.1016/j.amjcard.2018.08.050. Epub 2018 Sep 22.
Usefulness of screening for abdominal aortic aneurysm (AAA) during transthoracic echocardiography (TTE) in women is uncertain. The aim of the present study was to clarify the clinical usefulness of screening for AAA during TTE and to identify important TTE indices associated with AAA in women in a routine clinical setting. We prospectively studied 1,495 women (≥50 years) referred for TTE. AAA was defined as ≥30 mm in size. The additional screening time for AAA was <1 minute. The abdominal aorta was visualized in 95.1 % (1,422 of 1,495) using the same TTE probe. AAA was identified in 1.9% (27 of 1422). The aortic root size was larger in patients with AAA than those without (33.3 ± 3.2 vs 30.5 ± 3.4 mm, p < 0.001). The aortic root size had a correlation with abdominal aortic size (r = 0.22, p < 0.001). The aortic root size of ≥30.3 mm was predictive of AAA (area under the curve = 0.74, p < 0.001) and all patients with AAA had the aortic root size of ≥28.0 mm. Multiple logistic regression analysis revealed that the aortic root size (Odds ratio 1.17, p = 0.007) was a most independent TTE index of AAA. In conclusion, the visibility of the abdominal aorta using TTE probe was excellent. When the aortic root size is ≥28.0 mm during TTE in women ≥50 years of age, screening for AAA should be carried out.
经胸超声心动图（TTE）筛查女性腹主动脉瘤（AAA）的作用尚不确定。本研究旨在明确 TTE 筛查 AAA 的临床作用，并确定在常规临床环境中与女性 AAA 相关的重要 TTE 指标。我们前瞻性研究了 1495 名（≥50 岁）因 TTE 就诊的女性。AAA 定义为≥30mm。AAA 的额外筛查时间<1 分钟。使用相同的 TTE 探头，95.1%（1422/1495）的女性可显示腹主动脉。在 1422 名女性中发现 1.9%（27 名）患有 AAA。与无 AAA 的患者相比，AAA 患者的主动脉根部更大（33.3±3.2 vs. 30.5±3.4mm，p<0.001）。主动脉根部大小与腹主动脉大小相关（r=0.22，p<0.001）。主动脉根部大小≥30.3mm 可预测 AAA（曲线下面积=0.74，p<0.001），所有 AAA 患者的主动脉根部大小均≥28.0mm。多因素逻辑回归分析显示，主动脉根部大小（比值比 1.17，p=0.007）是 AAA 的最独立 TTE 指标。总之，TTE 探头对腹主动脉的显示极佳。当女性（≥50 岁）TTE 时主动脉根部大小≥28.0mm 时，应进行 AAA 筛查。
