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股神经阻滞或局部浸润镇痛用于全膝关节置换术后疼痛控制?一项随机对照试验的系统评价和荟萃分析。

Adductor Canal Block or Local Infiltrate Analgesia for Pain Control After Total Knee Arthroplasty? A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

机构信息

Adult Reconstruction, Hofstra School of Medicine, Lenox Hill Hospital, New York, NY.

School of Rehabilitation Sciences, McMaster University, Hamilton, ON, Canada.

出版信息

J Arthroplasty. 2019 Jan;34(1):183-189. doi: 10.1016/j.arth.2018.09.083. Epub 2018 Sep 28.

Abstract

BACKGROUND

Total knee arthroplasty is a treatment option for debilitating arthritis. In the postoperative period, patients experience moderate to severe pain affecting the rehabilitation, hospital stay, and patient satisfaction. This study aims at utilizing current best evidence to determine whether adductor canal block (ACB) or periarticular injection (PAI) is a better modality for managing short-term postoperative pain and opioid consumption.

METHODS

Embase, MEDLINE, HealthStar, Emcare, and PubMed were searched for randomized controlled trials from 1946 to August 2018, for literature addressing the comparison of ACB and PAI for pain management in the setting of total knee arthroplasty. A systematic review and meta-analysis were performed.

RESULTS

Six studies were included in our meta-analysis. When examining the combined visual analog scale (VAS) pain values for each group, analysis demonstrated greater reduction in scores for the PAI group, and the difference was statistically significant (P = .001). When comparing the VAS scores of subgroups analyzed at specific periods in time, there was a trend toward lower VAS scores in subgroups analyzed at 24 hours and 48 hours postoperatively (at rest and at movement) in the PAI group. Overall opioid consumption was lower in the PAI group, with demonstrated statistical significance (P = .03). When comparing the postoperative subgroups, there was a trend toward decreased opioid use in the PAI group, with 13.25% less opioid use at 48 hours and 9.5% less opioid use at 24 hours.

CONCLUSION

PAI could significantly improve postoperative pain and opioid consumption when compared with ACB. Additional, high-quality studies are required to further address this topic.

摘要

背景

全膝关节置换术是治疗致残性关节炎的一种选择。在术后期间,患者会经历中度到重度疼痛,这会影响康复、住院时间和患者满意度。本研究旨在利用当前最佳证据来确定收肌管阻滞(ACB)或关节周围注射(PAI)是否是管理短期术后疼痛和阿片类药物消耗的更好方式。

方法

从 1946 年到 2018 年 8 月,我们在 Embase、MEDLINE、HealthStar、Emcare 和 PubMed 上搜索了随机对照试验,以查找有关全膝关节置换术后管理中 ACB 和 PAI 比较的文献。进行了系统评价和荟萃分析。

结果

我们的荟萃分析纳入了 6 项研究。当检查每组的联合视觉模拟评分(VAS)疼痛值时,分析表明 PAI 组的评分降低幅度更大,差异具有统计学意义(P=.001)。当比较按特定时间段分析的亚组的 VAS 评分时,PAI 组在术后 24 小时和 48 小时(休息时和运动时)的亚组的 VAS 评分有降低的趋势。PAI 组的总体阿片类药物消耗量较低,具有统计学意义(P=.03)。当比较术后亚组时,PAI 组的阿片类药物使用量呈下降趋势,在 48 小时时减少了 13.25%,在 24 小时时减少了 9.5%。

结论

与 ACB 相比,PAI 可显著改善术后疼痛和阿片类药物的消耗。需要更多高质量的研究来进一步解决这个问题。

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