From the Department of Obstetrics and Gynecology and Women's Health, University of Louisville School of Medicine.
Department of Bioinformatics & Biostatistics, University of Louisville School of Public Health and Information Sciences, Louisville, KY.
Female Pelvic Med Reconstr Surg. 2020 Sep;26(9):563-569. doi: 10.1097/SPV.0000000000000621.
Women with gynecologic cancer may also present with pelvic floor dysfunction that can have a significant effect on quality of life. Combined surgical intervention for both malignancy and pelvic floor dysfunction may improve quality of life with minimal additional risk. We sought to determine the safety, feasibility, and frequency of combined gynecologic cancer surgery and surgery for pelvic floor dysfunction.
This is a retrospective cohort study that utilized the National Surgical Quality Improvement Program database provided through the American College of Surgeons. The National Surgical Quality Improvement Program database was queried for patients with a final diagnosis of gynecologic malignancy from 2011 to 2015. Common Procedural Terminology codes for gynecologic oncology procedures and pelvic floor dysfunction surgery were used to identify the study population. Baseline demographics and postoperative complications were abstracted from the database for these patients and compared for patients with combined surgeries versus gynecologic cancer surgeries alone.
One hundred twenty-nine women underwent combined procedures compared with 25,838 women undergoing gynecologic cancer surgery alone. Patients who underwent combined procedures were older, had lower body mass index, had higher preoperative albumin and hematocrit, and lower morbidity estimates (P < 0.05). Mean operative time was longer (226.4 vs 174.4 minutes, P < 0.01). There were no statistically significant differences in race, ethnicity, or medical comorbidities. There were no statistically significant differences in postoperative complications or readmissions between the 2 groups (P > 0.1).
Combined gynecologic cancer and pelvic floor dysfunction procedures are feasible and can safely be performed without differences in postoperative complications in appropriately selected patients.
患有妇科癌症的女性也可能出现盆底功能障碍,这会对生活质量产生重大影响。对恶性肿瘤和盆底功能障碍同时进行联合手术干预可能会改善生活质量,且风险最小。我们旨在确定妇科癌症手术和盆底功能障碍手术联合治疗的安全性、可行性和频率。
这是一项回顾性队列研究,利用美国外科医师学院提供的国家外科质量改进计划数据库。通过美国外科医师学院查询了 2011 年至 2015 年患有妇科恶性肿瘤的患者的最终诊断的国家外科质量改进计划数据库。使用妇科肿瘤学程序和盆底功能障碍手术的常见程序术语 (CPT) 代码来识别研究人群。从数据库中提取这些患者的基线人口统计学和术后并发症,并将这些患者的联合手术与妇科癌症手术单独进行比较。
129 名女性接受了联合手术,而 25838 名女性仅接受了妇科癌症手术。接受联合手术的患者年龄较大,体重指数较低,术前白蛋白和红细胞压积较高,发病率估计值较低(P<0.05)。平均手术时间较长(226.4 分钟比 174.4 分钟,P<0.01)。两组患者在种族、民族或合并症方面无统计学差异。两组术后并发症或再入院率无统计学差异(P>0.1)。
在适当选择的患者中,联合妇科癌症和盆底功能障碍手术是可行的,并且可以安全进行,而术后并发症没有差异。