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2
A Randomized Controlled Exploratory Pilot Study to Evaluate the Effect of Rotigotine Transdermal Patch on Parkinson's Disease-Associated Chronic Pain.一项评估罗替戈汀透皮贴剂对帕金森病相关慢性疼痛影响的随机对照探索性初步研究。
J Clin Pharmacol. 2016 Jul;56(7):852-61. doi: 10.1002/jcph.678. Epub 2015 Dec 31.
3
Effects of Night-Time Use of Rotigotine on Nocturnal Symptoms in Parkinson's Disease.夜间使用罗替戈汀对帕金森病夜间症状的影响。
Parkinsons Dis. 2015;2015:475630. doi: 10.1155/2015/475630. Epub 2015 Oct 21.
4
Prolonged-release oxycodone-naloxone for treatment of severe pain in patients with Parkinson's disease (PANDA): a double-blind, randomised, placebo-controlled trial.盐酸羟考酮-纳洛酮缓释片治疗帕金森病患者重度疼痛(PANDA)的双盲、随机、安慰剂对照试验。
Lancet Neurol. 2015 Dec;14(12):1161-70. doi: 10.1016/S1474-4422(15)00243-4. Epub 2015 Oct 19.
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A clinical survey of pain in Parkinson's disease in Eastern China.中国东部帕金森病疼痛的临床调查
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Associations of pain and depression with marital status in patients diagnosed with Parkinson's disease.帕金森病患者疼痛及抑郁与婚姻状况的关联
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Mov Disord. 2015 Oct;30(12):1623-31. doi: 10.1002/mds.26270. Epub 2015 Jun 11.
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Pain in multiple system atrophy and progressive supranuclear palsy compared to Parkinson's disease.与帕金森病相比,多系统萎缩和进行性核上性麻痹中的疼痛。
Brain Behav. 2015 May;5(5):e00320. doi: 10.1002/brb3.320. Epub 2015 Mar 25.
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Deep brain stimulation of the subthalamic nucleus improves pain in Parkinson's disease.丘脑底核的深部脑刺激可改善帕金森病的疼痛。
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帕金森病疼痛评定量表:批判与建议

Rating Scales for Pain in Parkinson's Disease: Critique and Recommendations.

作者信息

Perez-Lloret Santiago, Ciampi de Andrade Daniel, Lyons Kelly E, Rodríguez-Blázquez Carmen, Chaudhuri Kallol Ray, Deuschl Guenther, Cruccu Girgio, Sampaio Cristina, Goetz Christopher G, Schrag Anette, Martinez-Martin Pablo, Stebbins Glenn

机构信息

Institute of Cardiology Research University of Buenos Aires, National Research Council (CONICET-ININCA) Buenos Aires Argentina.

Centro de Dor Departamento de Neurologia da Faculdade de Medicina da Universidade de São Paulo São Paulo Brazil.

出版信息

Mov Disord Clin Pract. 2016 Jun 24;3(6):527-537. doi: 10.1002/mdc3.12384. eCollection 2016 Nov-Dec.

DOI:10.1002/mdc3.12384
PMID:30363588
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6178703/
Abstract

BACKGROUND

We aimed at critically appraising the clinimetric properties of existing pain scales or questionnaires and to give recommendations for their use in Parkinson's disease (PD).

METHODS

Clinimetric properties of pain scales used in PD were systematically evaluated. A scale was classified as 'recommended' if was used in PD, showed adequate clinimetric properties, and had been used by investigators other than the original developers; as 'suggested' if it was used in PD and fulfilled only one other criterion; and as 'listed' if it was used in PD but did not meet the other criteria. Only scales rating pain intensity or for syndromic classification were assessed.

RESULTS

Eleven of the 34 scales initially considered fulfilled inclusion criteria. Among the scales rating pain intensity, the "Brief Pain Inventory short form," "McGill Pain Questionnaire short and long forms," "Neuropathic Pain Symptoms Inventory," "11-point Numeric Rating Scale," "10-cm Visual Analog Scale," and "Pain-O-Meter" were "recommended with caution" because of lack of clinimetric data in PD, whereas the "King's PD Pain Scale" was "recommended." Among scales for pain syndromic classification, the "DN4" was "recommended with caution" because of lack of clinimetric data in PD; the "Leeds Assessment of Neuropathic Symptoms and Signs," "Pain-DETECT," and the "King's PD Pain Scale" were "suggested."

CONCLUSIONS

King's PD pain scale can be recommended for the assessment of pain intensity in PD. Syndromic classification of pain in PD may be achieved by the DN4, but clinimetric data in PD are needed for this scale.

摘要

背景

我们旨在严格评估现有疼痛量表或问卷的测量学特性,并为其在帕金森病(PD)中的应用提供建议。

方法

系统评估了用于PD的疼痛量表的测量学特性。如果一个量表在PD中使用,显示出足够的测量学特性,并且被原始开发者以外的研究者使用,则被归类为“推荐”;如果它在PD中使用且仅满足其他一个标准,则被归类为“建议”;如果它在PD中使用但未满足其他标准,则被归类为“列出”。仅评估了评定疼痛强度或用于综合征分类的量表。

结果

最初考虑的34个量表中有11个符合纳入标准。在评定疼痛强度的量表中,“简明疼痛问卷简表”“麦吉尔疼痛问卷简表和长表”“神经病理性疼痛症状量表”“11点数字评定量表”“10厘米视觉模拟量表”和“疼痛计”因在PD中缺乏测量学数据而“谨慎推荐”,而“国王帕金森病疼痛量表”则“推荐使用”。在用于疼痛综合征分类的量表中,“DN4”因在PD中缺乏测量学数据而“谨慎推荐”;“利兹神经病理性症状和体征评估量表”“疼痛检测量表”和“国王帕金森病疼痛量表”“建议使用”。

结论

国王帕金森病疼痛量表可推荐用于评估PD患者的疼痛强度。DN4量表可用于PD患者疼痛的综合征分类,但该量表在PD中的测量学数据仍需完善。