• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

慢性椎间盘源性下腰痛的影响:成本与患者负担

The Impact of Chronic Discogenic Low Back Pain: Costs and Patients' Burden.

作者信息

Geurts José W, Willems Paul C, Kallewaard Jan-Willem, van Kleef Maarten, Dirksen Carmen

机构信息

Department of Anesthesiology and Pain Medicine, Maastricht University Medical Centre, Maastricht, Netherlands.

Department of Anesthesiology and Pain Management, Rijnstate Hospital, Arnhem, Netherlands.

出版信息

Pain Res Manag. 2018 Oct 1;2018:4696180. doi: 10.1155/2018/4696180. eCollection 2018.

DOI:10.1155/2018/4696180
PMID:30364097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6188764/
Abstract

INTRODUCTION

Chronic discogenic low back pain (CDP) is frequently diagnosed in patients referred to specialized pain clinics for their back pain. The aim of this study is to assess the impact of CDP both on the individual patient and on society.

MATERIALS AND METHODS

Using the baseline records of 80 patients in a randomized trial assessing the effectiveness of a new intervention for CDP, healthcare and societal costs related to back pain are calculated. Furthermore, the impact of the condition on perceived pain, disability, health-related quality of life, Quality of life Adjusted Life Years (QALY), and QALY loss is assessed.

RESULTS

Using the friction costs approach, we found that the annual costs for society are €7,911.95 per CDP patient, 51% healthcare and 49% societal costs. When using the human capital approach, total costs were €18,940.58, 22% healthcare and 78% societal costs. Healthcare costs were mainly related to pain treatment. Mean pain severity was 6.5 (0-10), and 46% suffered from severe pain (≥7/10). Mean physical limitations rate was 43.7; 13.5% of the patients were very limited to disabled. QALY loss compared to a healthy population was 64%.

DISCUSSION

This study shows that in patients with CDP referred to a pain clinic, costs for society are high and the most used healthcare resources are pain therapies. Patients suffer severe pain, are physically limited, and experience a serious loss in quality of life.

摘要

引言

慢性椎间盘源性下腰痛(CDP)在因背痛前往专科疼痛诊所就诊的患者中经常被诊断出来。本研究的目的是评估CDP对个体患者和社会的影响。

材料与方法

利用一项评估CDP新干预措施有效性的随机试验中80名患者的基线记录,计算与背痛相关的医疗保健和社会成本。此外,评估该疾病对感知疼痛、残疾、健康相关生活质量、质量调整生命年(QALY)和QALY损失的影响。

结果

采用摩擦成本法,我们发现每位CDP患者每年的社会成本为7911.95欧元,其中51%为医疗保健成本,49%为社会成本。采用人力资本法时,总成本为18940.58欧元,其中22%为医疗保健成本,78%为社会成本。医疗保健成本主要与疼痛治疗有关。平均疼痛严重程度为6.5(0 - 10),46%的患者遭受严重疼痛(≥7/10)。平均身体限制率为43.7;13.5%的患者非常受限至残疾。与健康人群相比,QALY损失为64%。

讨论

本研究表明,在转诊至疼痛诊所的CDP患者中,社会成本很高,最常用的医疗保健资源是疼痛治疗。患者遭受严重疼痛,身体受限,生活质量严重下降。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c2f/6188764/dbdd28445a65/PRM2018-4696180.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c2f/6188764/a026ffb5c809/PRM2018-4696180.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c2f/6188764/dbdd28445a65/PRM2018-4696180.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c2f/6188764/a026ffb5c809/PRM2018-4696180.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c2f/6188764/dbdd28445a65/PRM2018-4696180.002.jpg

相似文献

1
The Impact of Chronic Discogenic Low Back Pain: Costs and Patients' Burden.慢性椎间盘源性下腰痛的影响:成本与患者负担
Pain Res Manag. 2018 Oct 1;2018:4696180. doi: 10.1155/2018/4696180. eCollection 2018.
2
The longitudinal relationships between pain severity and disability versus health-related quality of life and costs among chronic low back pain patients.慢性腰痛患者的疼痛严重程度和残疾与健康相关的生活质量和成本之间的纵向关系。
Qual Life Res. 2020 Jan;29(1):275-287. doi: 10.1007/s11136-019-02302-w. Epub 2019 Sep 17.
3
Cost utility analysis of caudal epidural injections in the treatment of lumbar disc herniation, axial or discogenic low back pain, central spinal stenosis, and post lumbar surgery syndrome.腰间盘突出症、轴向或椎间盘源性下腰痛、中央型椎管狭窄症和腰椎术后综合征的骶管硬膜外注射治疗的成本效用分析。
Pain Physician. 2013 May-Jun;16(3):E129-43.
4
Efficacy and cost-effectiveness of intradiscal methylene blue injection for chronic discogenic low back pain: study protocol for a randomized controlled trial.椎间盘内注射亚甲蓝治疗慢性盘源性下腰痛的疗效及成本效益:一项随机对照试验的研究方案
Trials. 2015 Nov 21;16:532. doi: 10.1186/s13063-015-1058-6.
5
Personal and Societal Impact of Low Back Pain: The Groningen Spine Cohort.腰背疼痛的个人和社会影响:格罗宁根脊柱队列研究。
Spine (Phila Pa 1976). 2019 Dec 15;44(24):E1443-E1451. doi: 10.1097/BRS.0000000000003174.
6
Quality of life, resource consumption and costs of spinal cord stimulation versus conventional medical management in neuropathic pain patients with failed back surgery syndrome (PROCESS trial).脊髓刺激与传统药物治疗对腰椎手术失败综合征神经性疼痛患者的生活质量、资源消耗及成本的影响(PROCESS试验)
Eur J Pain. 2008 Nov;12(8):1047-58. doi: 10.1016/j.ejpain.2008.01.014. Epub 2008 Mar 21.
7
Effectiveness and cost-effectiveness of three types of physiotherapy used to reduce chronic low back pain disability: a pragmatic randomized trial with economic evaluation.三种用于减轻慢性下腰痛残疾的物理治疗方法的有效性和成本效益:一项带有经济评估的实用随机试验。
Spine (Phila Pa 1976). 2007 Jun 15;32(14):1474-81. doi: 10.1097/BRS.0b013e318067dc26.
8
Is exposure in vivo cost-effective for chronic low back pain? A trial-based economic evaluation.体内暴露疗法对慢性腰痛是否具有成本效益?一项基于试验的经济学评估。
BMC Health Serv Res. 2015 Dec 14;15:549. doi: 10.1186/s12913-015-1212-6.
9
Economic evaluation of an intensive group training protocol compared with usual care physiotherapy in patients with chronic low back pain.与常规护理物理治疗相比,针对慢性下腰痛患者的强化小组训练方案的经济学评估。
Spine (Phila Pa 1976). 2008 Feb 15;33(4):445-51. doi: 10.1097/BRS.0b013e318163fa59.
10
The relationship between pain, disability, quality of life and cognitive-behavioural factors in chronic back pain.慢性背痛患者的疼痛、残疾、生活质量与认知行为因素之间的关系。
Disabil Rehabil. 2012;34(23):1993-2000. doi: 10.3109/09638288.2012.667187. Epub 2012 Mar 30.

引用本文的文献

1
Association between lifestyle-related factors and low back pain: Evidence from a Japanese population-based study.生活方式相关因素与腰痛之间的关联:来自一项日本人群研究的证据。
PLoS One. 2025 Jul 30;20(7):e0328684. doi: 10.1371/journal.pone.0328684. eCollection 2025.
2
Assessment of muscle fiber types transformation in rats with discogenic low back pain using diffusion tensor image of paraspinal muscles.利用椎旁肌扩散张量成像评估椎间盘源性下腰痛大鼠的肌纤维类型转变
BMC Med Imaging. 2025 May 21;25(1):177. doi: 10.1186/s12880-025-01706-0.
3
Routine measurement in low back pain; towards a pragmatic patient-reported productivity cost outcome measurement using the institute for medical technology assessment productivity cost questionnaire.

本文引用的文献

1
A Profile of Low Back Pain: Treatment and Costs Associated With Patients Referred to Orthopedic Specialists in Sweden.腰痛患者概况:在瑞典转介至骨科专家的患者的治疗和费用。
Spine (Phila Pa 1976). 2017 Sep 1;42(17):1302-1310. doi: 10.1097/BRS.0000000000002089.
2
Medical specialists care and hospital costs for low back pain in the Netherlands.荷兰下背痛的医学专家护理及医院费用。
Eur J Pain. 2017 Apr;21(4):705-715. doi: 10.1002/ejp.974. Epub 2016 Nov 8.
3
Diagnosis and Characters of Non-Specific Low Back Pain in Japan: The Yamaguchi Low Back Pain Study.
腰痛的常规测量;使用医学技术评估机构生产力成本问卷实现实用的患者报告生产力成本结果测量。
Eur J Health Econ. 2025 Feb 21. doi: 10.1007/s10198-025-01756-9.
4
Lumbar Facet Joint Radiofrequency Ablation With a 3-Tined Cannula: A Technical Report and Observational Study.使用三齿套管进行腰椎小关节射频消融:技术报告与观察性研究
Pain Res Manag. 2024 Dec 20;2024:8871568. doi: 10.1155/prm/8871568. eCollection 2024.
5
Drug retention after intradiscal administration.椎间盘内给药后的药物滞留。
Drug Deliv. 2024 Dec;31(1):2415579. doi: 10.1080/10717544.2024.2415579. Epub 2024 Oct 20.
6
Evaluation of chiropractic students' knowledge and attitudes following pain interventions: A randomized educational trial at 2 institutions.整脊疗法学生在疼痛干预后的知识与态度评估:两所机构的随机教育试验
J Chiropr Educ. 2024 Oct 23;38(2):106-113. doi: 10.7899/JCE-23-22.
7
Effectiveness of intradiscal platelet rich plasma for discogenic low back pain without Modic changes: A randomized controlled trial.椎间盘内注射富血小板血浆治疗无Modic改变的盘源性下腰痛的有效性:一项随机对照试验。
Interv Pain Med. 2022 Jan 21;1(1):100011. doi: 10.1016/j.inpm.2022.100011. eCollection 2022 Mar.
8
Prediction of transforaminal epidural injection success in sciatica (POTEISS): a protocol for the development of a multivariable prediction model for outcome after transforaminal epidural steroid injection in patients with lumbar radicular pain due to disc herniation or stenosis.经椎间孔硬膜外注射治疗坐骨神经痛(POTEISS)的预测:腰椎间盘突出症或狭窄引起的腰椎神经根痛患者行经椎间孔硬膜外类固醇注射后结局的多变量预测模型开发方案。
BMC Neurol. 2024 Aug 20;24(1):290. doi: 10.1186/s12883-024-03801-1.
9
Association of Muscle Strength, Psychological Factors, and Central Sensitization With Movement-Evoked Pain in Patients With Nonspecific Chronic Low Back Pain: The BACKFIT Project.非特异性慢性下腰痛患者的肌肉力量、心理因素和中枢敏化与运动诱发疼痛的关联:BACKFIT项目
Sports Health. 2025 Mar;17(2):342-350. doi: 10.1177/19417381241235152. Epub 2024 Apr 2.
10
Screening patients requiring secondary lumbar surgery for degenerative lumbar spine diseases: a nationwide sample cohort study.对需要进行二次腰椎手术的退变性腰椎疾病患者进行筛选:一项全国性样本队列研究。
Sci Rep. 2024 Jan 14;14(1):1295. doi: 10.1038/s41598-024-51861-7.
日本非特异性腰痛的诊断与特征:山口腰痛研究
PLoS One. 2016 Aug 22;11(8):e0160454. doi: 10.1371/journal.pone.0160454. eCollection 2016.
4
A burden of illness study for neuropathic pain in Europe.欧洲神经性疼痛的疾病负担研究。
Clinicoecon Outcomes Res. 2016 Apr 27;8:113-26. doi: 10.2147/CEOR.S81396. eCollection 2016.
5
Efficacy and cost-effectiveness of intradiscal methylene blue injection for chronic discogenic low back pain: study protocol for a randomized controlled trial.椎间盘内注射亚甲蓝治疗慢性盘源性下腰痛的疗效及成本效益:一项随机对照试验的研究方案
Trials. 2015 Nov 21;16:532. doi: 10.1186/s13063-015-1058-6.
6
Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.1990年至2013年188个国家301种急慢性疾病和损伤的全球、区域及国家发病率、患病率和伤残调整生命年:全球疾病负担研究2013的系统分析
Lancet. 2015 Aug 22;386(9995):743-800. doi: 10.1016/S0140-6736(15)60692-4. Epub 2015 Jun 7.
7
Costs and cost-effectiveness of epidural steroids for acute lumbosacral radicular syndrome in general practice: an economic evaluation alongside a pragmatic randomized control trial.全科医疗中硬膜外注射类固醇治疗急性腰骶神经根综合征的成本及成本效益:一项与实用随机对照试验同步进行的经济学评估
Spine (Phila Pa 1976). 2014 Nov 15;39(24):2007-12. doi: 10.1097/BRS.0000000000000597.
8
A modified Delphi survey on the signs and symptoms of low back pain: indicators for an interventional management approach.一项关于腰痛体征和症状的改良德尔菲调查:介入性管理方法的指标
Pain Pract. 2015 Jan;15(1):12-21. doi: 10.1111/papr.12135. Epub 2013 Dec 9.
9
The cost of chronic pain: an analysis of a regional pain management service in Ireland.慢性疼痛的成本:爱尔兰一项区域疼痛管理服务的分析
Pain Med. 2013 Oct;14(10):1518-28. doi: 10.1111/pme.12202. Epub 2013 Aug 14.
10
Lumbar discogenic pain: state-of-the-art review.腰椎间盘源性疼痛:最新研究综述。
Pain Med. 2013 Jun;14(6):813-36. doi: 10.1111/pme.12082. Epub 2013 Apr 8.