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梭状芽孢杆菌在一名创伤患者中引起恶性水肿:病例报告及文献综述

Clostridium causing malignant edema in a trauma patient: a case report and review of literature.

作者信息

Gray Sanjiv Fitz-Morris, Dieudonne Beatrice Esther

机构信息

University of Central Florida, Osceola Regional Medical Center, Orlando, Florida, USA.

出版信息

Pan Afr Med J. 2018 Jun 12;30:118. doi: 10.11604/pamj.2018.30.118.14156. eCollection 2018.

DOI:10.11604/pamj.2018.30.118.14156
PMID:30364449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6195232/
Abstract

Clostridium infection is a rare but potentially lethal infection associated with abortions, injury, contaminated wounds, and illicit drug use. It causes a recognizable syndrome with marked leukocytosis. Rapid diagnosis and aggressive sepsis management is required for optimal outcome. We report a case in a trauma patient with delayed presentation after sustaining facial trauma with soil contamination. The critical care management is summarized and a review of the literature.

摘要

梭菌感染是一种罕见但可能致命的感染,与流产、受伤、伤口污染及非法药物使用有关。它会引发一种伴有明显白细胞增多的可识别综合征。为获得最佳治疗效果,需要快速诊断并积极进行脓毒症管理。我们报告一例创伤患者,其面部受土壤污染创伤后就诊延迟。总结了重症监护管理情况并对文献进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09ce/6195232/78516a9f6e5b/PAMJ-30-118-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09ce/6195232/9f72898a5799/PAMJ-30-118-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09ce/6195232/78516a9f6e5b/PAMJ-30-118-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09ce/6195232/9f72898a5799/PAMJ-30-118-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09ce/6195232/78516a9f6e5b/PAMJ-30-118-g002.jpg

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本文引用的文献

1
Clostridium sordellii infection: epidemiology, clinical findings, and current perspectives on diagnosis and treatment.索氏梭菌感染:流行病学、临床发现以及诊断与治疗的当前观点
Clin Infect Dis. 2006 Dec 1;43(11):1436-46. doi: 10.1086/508866. Epub 2006 Oct 30.
2
Fatal toxic shock syndrome associated with Clostridium sordellii after medical abortion.药物流产后与索氏梭菌相关的致命性中毒性休克综合征
N Engl J Med. 2005 Dec 1;353(22):2352-60. doi: 10.1056/NEJMoa051620.
3
The toxins responsible for the lesions of Clostridium sordelli gas gangrene.
J Med Microbiol. 1969 Feb;2(1):37-53. doi: 10.1099/00222615-2-1-37.
4
Clostridial bacteremia in cancer patients. A 12-year experience.癌症患者的梭菌血症。12年的经验。
Cancer. 1991 Apr 1;67(7):1928-42. doi: 10.1002/1097-0142(19910401)67:7<1928::aid-cncr2820670718>3.0.co;2-9.