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药物流产后与索氏梭菌相关的致命性中毒性休克综合征

Fatal toxic shock syndrome associated with Clostridium sordellii after medical abortion.

作者信息

Fischer Marc, Bhatnagar Julu, Guarner Jeannette, Reagan Sarah, Hacker Jill K, Van Meter Sharon H, Poukens Vadims, Whiteman David B, Iton Anthony, Cheung Michele, Dassey David E, Shieh Wun-Ju, Zaki Sherif R

机构信息

Centers for Disease Control and Prevention, Atlanta, USA.

出版信息

N Engl J Med. 2005 Dec 1;353(22):2352-60. doi: 10.1056/NEJMoa051620.

Abstract

Endometritis and toxic shock syndrome associated with Clostridium sordellii have previously been reported after childbirth and, in one case, after medical abortion. We describe four deaths due to endometritis and toxic shock syndrome associated with C. sordellii that occurred within one week after medically induced abortions. Clinical findings included tachycardia, hypotension, edema, hemoconcentration, profound leukocytosis, and absence of fever. These cases indicate the need for physician awareness of this syndrome and for further study of its association with medical abortion.

摘要

此前曾有报道称,分娩后以及有一例是在药物流产后出现了与索氏梭菌相关的子宫内膜炎和中毒性休克综合征。我们描述了4例与索氏梭菌相关的子宫内膜炎和中毒性休克综合征导致的死亡病例,这些病例发生在药物流产后一周内。临床症状包括心动过速、低血压、水肿、血液浓缩、严重白细胞增多以及无发热症状。这些病例表明,医生需要了解这种综合征,并对其与药物流产的关联进行进一步研究。

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