Boyd Carter, Wood Kyle, Whitaker Dustin, Assimos Dean G
University of Alabama-Birmingham School of Medicine, Birmingham, AL, USA.
Department of Urology, University of Alabama-Birmingham, Birmingham, AL, USA.
Asian J Urol. 2018 Oct;5(4):215-222. doi: 10.1016/j.ajur.2018.06.002. Epub 2018 Jun 8.
The prevalence of kidney stone disease is increasing, afflicting 7%-11% of the United States population. Multiple systemic conditions, including obesity and diabetes, are also on the rise. Further, the literature has demonstrated a strong association between metabolic syndrome, its components, and kidney stone disease. In this article, we aim to review the associations of metabolic syndrome and nephrolithiasis, discussing the pathophysiology, urinary parameters, and clinical presentations. With this knowledge, urologists will have a more comprehensive understanding of this complex population of metabolic stone formers enabling improved patient management and treatment of stone disease.
肾结石疾病的患病率正在上升，困扰着7%至11%的美国人口。包括肥胖和糖尿病在内的多种全身性疾病也在增加。此外，文献表明代谢综合征及其组成成分与肾结石疾病之间存在密切关联。在本文中，我们旨在综述代谢综合征与肾结石的关联，讨论其病理生理学、尿液参数和临床表现。有了这些知识，泌尿外科医生将对这一复杂的代谢性结石形成人群有更全面的了解，从而能够改善患者管理和结石疾病的治疗。
