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美国痴呆症患病率和风险因素趋势中的种族和民族差异。

Racial and ethnic differences in trends in dementia prevalence and risk factors in the United States.

作者信息

Chen Cynthia, Zissimopoulos Julie M

机构信息

Leonard D. Schaeffer Center for Health Policy and Economics, Price School of Public Policy, University of Southern California, Los Angeles, United States of America.

Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.

出版信息

Alzheimers Dement (N Y). 2018 Oct 5;4:510-520. doi: 10.1016/j.trci.2018.08.009. eCollection 2018.

Abstract

INTRODUCTION

Disparities in dementia prevalence across racial/ethnic groups in the United States may not be narrowing over time.

METHODS

Data from Health and Retirement Study (2000 to 2012) were analyzed. Dementia was ascertained based on cognitive, functional measures. Logistic regression was used to quantify association between dementia and risk factors, including chronic conditions, use of drug treatment for them, separately for whites, blacks, and Hispanics.

RESULTS

Disparities in dementia prevalence declined between blacks and whites and increased between Hispanics and whites. Adjusting for risk factors reduced but did not eliminate disparities. Compared to no hypertension, untreated hypertension was associated with increased risk of dementia for all racial/ethnic groups while treated hypertension was associated with reduced risk for whites. Diabetes treated with oral drugs was not associated with increased dementia risk.

DISCUSSION

Racial disparities in dementia may be reduced by prevention and management of disease and promoting educational attainment among blacks and Hispanics.

摘要

引言

美国不同种族/族裔群体之间痴呆症患病率的差异可能不会随着时间的推移而缩小。

方法

对健康与退休研究(2000年至2012年)的数据进行了分析。根据认知和功能测量来确定痴呆症。使用逻辑回归来量化痴呆症与风险因素之间的关联,包括慢性病及其药物治疗情况,分别针对白人、黑人和西班牙裔进行分析。

结果

黑人和白人之间痴呆症患病率的差异有所下降,而西班牙裔和白人之间的差异有所增加。对风险因素进行调整后,差异有所减少但并未消除。与无高血压相比,未经治疗的高血压与所有种族/族裔群体患痴呆症的风险增加相关,而经过治疗的高血压与白人患痴呆症的风险降低相关。口服药物治疗的糖尿病与痴呆症风险增加无关。

讨论

通过疾病的预防和管理以及提高黑人和西班牙裔的教育水平,可能会减少痴呆症的种族差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b789/6197734/c347c633ceda/gr1.jpg

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