Andrus Gerontology Center, 5116University of Southern California, Los Angeles, CA, USA.
J Aging Health. 2023 Mar;35(3-4):209-220. doi: 10.1177/08982643221120743. Epub 2022 Aug 19.
This study examined differences in accelerated biological aging among non-Hispanic Blacks, Hispanics, and non-Hispanic Whites in the United States and assessed whether including life course socioeconomic conditions attenuated observed racial/ethnic differences. Data came from the Venous Blood Collection Subsample of the Health and Retirement Study. We used a comprehensive summary measure of biological age (BA-22). We determined whether key lifetime socioeconomic conditions contributed to racial/ethnic differences in biological aging. Findings indicated that non-Hispanic Blacks and Hispanics have accelerated aging, and non-Hispanic Whites have decelerated aging. Racial/ethnic differences were strongly tied to educational attainment. We also observed a significant difference by birthplace for Hispanics. US-born Hispanics had accelerated biological aging, whereas foreign-born Hispanics did not. In age-stratified analyses, these racial/ethnic differences were found for adults aged 56-74, but not for adults aged 75+. These findings provide insight into biological differences underlying racial/ethnic disparities in health.
本研究考察了美国非西班牙裔黑种人、西班牙裔人和非西班牙裔白种人之间加速的生物衰老差异，并评估了纳入生命历程社会经济状况是否会减弱观察到的种族/民族差异。数据来自健康与退休研究的静脉采血抽样。我们使用了一种综合的生物年龄综合衡量标准（BA-22）。我们确定了关键的终身社会经济状况是否对生物衰老的种族/民族差异有影响。研究结果表明，非西班牙裔黑人和西班牙裔人的衰老速度加快，而非西班牙裔白种人的衰老速度则减缓。种族/民族差异与受教育程度密切相关。我们还观察到西班牙裔人的出生地存在显著差异。出生于美国的西班牙裔人存在加速的生物衰老，而出生于国外的西班牙裔人则没有。在年龄分层分析中，这种种族/民族差异在 56-74 岁的成年人中存在，但在 75 岁以上的成年人中不存在。这些发现为健康方面的种族/民族差异的生物学基础提供了深入了解。
