Fitzgibbons Patrick L
Department of Pathology, St. Jude Medical Center, Fullerton, CA 92835, United States.
Semin Diagn Pathol. 2018 Nov;35(6):370-380. doi: 10.1053/j.semdp.2018.10.002. Epub 2018 Oct 16.
The alimentary tract serves as host to a large number of diseases. In the non-neoplastic group of disorders, conventional histochemistry continues to play an important diagnostic role. It is particularly important in recognizing specific infectious diseases, such as Helicobacter gastritis, Whipple disease, intestinal tuberculosis and other forms of mycobacteriosis, malakoplakia, intestinal spirochetosis, fungal enteritides, amebiasis, cryptosporidiosis, isosporiasis, and microsporidiosis. Those conditions and their histochemical properties are discussed in this review, along with the use of histochemistry in the characterization of structural gastrointestinal disorders. The latter include mucosal metaplasias, amyloidosis, glycogenic acanthosis of the esophagus, lymphocytic-collagenous colitis, gastric neuroendocrine hyperplasia, and pill gastritis.
消化道是大量疾病的宿主。在非肿瘤性疾病组中，传统组织化学继续发挥重要的诊断作用。它在识别特定的传染病方面尤为重要，如幽门螺杆菌胃炎、惠普尔病、肠结核和其他形式的分枝杆菌病、软斑病、肠道螺旋体病、真菌性肠炎、阿米巴病、隐孢子虫病、等孢子球虫病和微孢子虫病。本文综述了这些疾病及其组织化学特性，以及组织化学在结构性胃肠疾病特征描述中的应用。后者包括黏膜化生、淀粉样变性、食管糖原棘皮症、淋巴细胞性胶原性结肠炎、胃神经内分泌增生和药物性胃炎。
