Ishikawa H, Isayama Y
Infect Immun. 1987 Jul;55(7):1607-9. doi: 10.1128/iai.55.7.1607-1609.1987.
The nature of the receptors for Bordetella bronchiseptica was investigated by using the in vitro adherence assay system. The results indicated that sialyl glycoconjugates acted as receptors on swine nasal mucosa. These results were obtained by two independent approaches: inhibition of epithelial cell adherence with sialic acid-containing compounds but not with compounds lacking sialic acid residues and loss of adherence after treatment of epithelial cells with periodate or neuraminidase. B. bronchiseptica seems to have strong affinity for mucin. This may help the bacterium to colonize the mucosal surfaces of the swine nasal cavity.
利用体外黏附试验系统研究了支气管败血波氏杆菌受体的性质。结果表明，唾液酸糖缀合物作为猪鼻黏膜上的受体。这些结果通过两种独立的方法获得：用含唾液酸的化合物而非缺乏唾液酸残基的化合物抑制上皮细胞黏附，以及用高碘酸盐或神经氨酸酶处理上皮细胞后黏附丧失。支气管败血波氏杆菌似乎对黏蛋白有很强的亲和力。这可能有助于该细菌在猪鼻腔黏膜表面定殖。
