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关于使用内部转录间隔区测序鉴定指间型毛癣菌/须癣毛癣菌错误的观点：迫切需要更新序列数据库。

Perspectives on misidentification of Trichophyton interdigitale/Trichophyton mentagrophytes using internal transcribed spacer region sequencing: Urgent need to update the sequence database.

机构信息

Department of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.

Department of Dermatology, Dr. RML Hospital and PGIMER, New Delhi, India.

出版信息

Mycoses. 2019 Jan;62(1):11-15. doi: 10.1111/myc.12865. Epub 2018 Nov 15.

DOI:10.1111/myc.12865
PMID:30367553
Abstract

The taxonomy of the dermatophytes has been revisited using a novel multilocus phylogenetic approach, and several neotypes and reference strains have been assigned for Trichophyton species. Single gene sequencing, that is the ITS region, for identification of highly related species T. mentagrophytes/T. interdigitale, warrant reassessment. The sequence database (Westerdijk and NCBI) needs to be updated as several incorrect/obsolete entries of reference and neotype strains of T. interdigitale/T. mentagrophytes hampers correct identification of this complex.

摘要

使用新型多基因系统发育分析方法重新研究了皮肤真菌的分类，为 Trichophyton 种指定了几个新拟种和参考菌株。用于鉴定高度相关的物种 T. mentagrophytes/T. interdigitale 的单基因测序，即 ITS 区，需要重新评估。由于 Westerdijk 和 NCBI 数据库中存在几个不正确/过时的 T. interdigitale/T. mentagrophytes 参考和新拟种菌株的条目，因此需要更新序列数据库，这会阻碍对该复合体的正确鉴定。

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