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“MicroHibro”:一款用于食品中预测微生物学和微生物风险评估的软件工具。

'MicroHibro': A software tool for predictive microbiology and microbial risk assessment in foods.

机构信息

Department of Food Science and Technology, Faculty of Veterinary, Agrifood Campus of International Excellence (ceiA3), University of Cordoba, 14014, Córdoba, Spain.

Department of Food Science and Technology, Faculty of Veterinary, Agrifood Campus of International Excellence (ceiA3), University of Cordoba, 14014, Córdoba, Spain.

出版信息

Int J Food Microbiol. 2019 Feb 2;290:226-236. doi: 10.1016/j.ijfoodmicro.2018.10.007. Epub 2018 Oct 10.

Abstract

A tool able to quantitatively assess the fate of potential pathogenic microorganisms in foods along the food chain and their impact on public health is highly valuable for food safety decision-makers. The aim of this work was to present an overview of the Predictive Microbiology software MicroHibro, which is able to assess the evolution of potential pathogens and spoilage microorganisms along the food chain, providing estimates for the exposure level and risk associated with a food product. The application is built on an extensive Predictive Microbiology Model Data Base (PMDB) including kinetic processes like growth, inactivation, transfer as well as dose-response models. PMDB can be populated with new models by using an on-line tool in combination with a standardized method for describing Predictive Microbiology models. This enables MicroHibro to be easily updated, increasing its applicability and use. Estimation of microbial risk associated with a food product can be achieved, in MicroHibro, by describing steps in any food chain using four different microbial processes (growth, inactivation, transfer and partitioning). As a result, an estimate of the concentration and prevalence of microorganisms in the food of interest as well as attendant risk are provided. Also, MicroHibro allows comparing different predictive models and validate them by introducing user's data. In this paper, examples are provided to illustrate how predictive models can be incorporated in MicroHibro, and then, used to develop a Quantitative Microbial Risk Assessment model. The use of expert computational systems is a powerful tool for supporting food safety and quality activities by Health Authorities and the food industry. They represent a breakthrough in the assessment and management of food safety based on scientific evidence.

摘要

对于食品安全决策者来说,能够定量评估食品链中潜在致病微生物的命运及其对公众健康的影响的工具具有很高的价值。本工作旨在概述能够评估食品链中潜在病原体和腐败微生物演变的预测微生物学软件 MicroHibro,为与食品相关的暴露水平和风险提供估计。该应用程序建立在一个广泛的预测微生物学模型数据库 (PMDB) 之上,其中包括生长、失活、转移以及剂量反应模型等动力学过程。PMDB 可以通过使用在线工具结合描述预测微生物学模型的标准化方法来填充新模型。这使得 MicroHibro 可以轻松更新,从而提高其适用性和使用性。通过使用四种不同的微生物过程(生长、失活、转移和分配)来描述任何食品链中的步骤,在 MicroHibro 中可以估计与食品相关的微生物风险。因此,提供了有关感兴趣食品中微生物的浓度和流行率以及相关风险的估计。此外,MicroHibro 允许通过引入用户数据来比较不同的预测模型并对其进行验证。本文提供了一些示例,说明如何将预测模型合并到 MicroHibro 中,然后用于开发定量微生物风险评估模型。专家计算系统的使用是支持卫生当局和食品行业食品安全和质量活动的有力工具。它们是基于科学证据评估和管理食品安全的突破。

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