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影像学在特发性肉芽肿性乳腺炎诊断中的应用:临床医生视角

Use of Imaging for the Diagnosis of Idiopathic Granulomatous Mastitis: A Clinician's Perspective.

作者信息

Hasbahceci Mustafa, Kadioglu Huseyin

机构信息

General Surgery Clinic, Medical Park Fatih Hospital, Fatih, Istanbul, Turkey.

General Surgery Clinic, Istanbul Medicana Hospital, Bahcelievler, Istanbul, Turkey.

出版信息

J Coll Physicians Surg Pak. 2018 Nov;28(11):862-867. doi: 10.29271/jcpsp.2018.11.862.

DOI:10.29271/jcpsp.2018.11.862
PMID:30369380
Abstract

Idiopathic granulomatous mastitis (IGM) is an inflammatory breast disease with unknown etiology and nonspecific symptoms. Differentiation of breast cancer from granulomatous disease is a diagnostic and clinical challenge. Imaging features and decision of the surgeon, based on these findings, may be important steps during diagnosis and follow-up period. Articles in association with imaging of IGM were evaluated using a PubMed search in August, 2017. Hypo-echoic or heterogeneous mass/es with or without tubular extensions were the most common ultrasonographic findings. Focal asymmetric density with or without skin thickening and parenchymal distortion were detected in most of the patients during mammography. Magnetic resonance imaging most commonly revealed focal or diffuse asymmetrical signal intensity changes without significant mass effect. Although a specified and standardised criteria list for each type of the imaging modality has been lacking, the most commonly detected imaging findings, especially in cases of multiple lesions in accordance with the decision of the surgeon and/or clinician, can be used for the diagnosis and follow-up of IGM with acceptable safety margins. However, in the presence of any suspicious findings during imaging or clinical examination, histopathological analysis should be performed.

摘要

特发性肉芽肿性乳腺炎(IGM)是一种病因不明、症状不特异的乳腺炎性疾病。鉴别乳腺癌与肉芽肿性疾病是一项诊断和临床挑战。基于这些发现的影像学特征及外科医生的判断,可能是诊断及随访期间的重要步骤。2017年8月通过PubMed检索对与IGM影像学相关的文章进行了评估。低回声或不均匀肿块伴或不伴管状延伸是最常见的超声检查结果。大多数患者在乳腺钼靶检查中发现有局灶性不对称密度影伴或不伴皮肤增厚及实质变形。磁共振成像最常显示局灶性或弥漫性不对称信号强度改变,无明显占位效应。尽管每种影像学检查方式都缺乏特定的标准化标准清单,但最常检测到的影像学表现,尤其是在存在多个病灶的情况下,根据外科医生和/或临床医生的判断,可用于IGM的诊断和随访,且具有可接受的安全范围。然而,在影像学检查或临床检查中出现任何可疑表现时,均应进行组织病理学分析。

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