Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark.
The National Research Centre for the Working Environment, Lersø Parkallé 105, 2100, Copenhagen, Denmark.
Int Arch Occup Environ Health. 2019 Feb;92(2):165-173. doi: 10.1007/s00420-018-1365-9. Epub 2018 Oct 28.
Only a few studies have investigated the impact of negative aspects of social relations on cognitive function, and they have shown mixed results. Conflicts at work are part of the negative aspects of social relations, but the impact of experiencing conflicts at work has not yet been investigated as a risk factor for dementia. Therefore, we investigated whether experiencing prolonged or serious conflicts with a supervisor or colleagues at work was associated with incident dementia in old age.
We analyzed data of 6,436 men and women from the third survey of the Copenhagen City Heart Study. At baseline in 1991-1994, the participants reported whether they had ever had a prolonged or serious conflict at work. The participants were followed until 2014. We used Poisson regression to estimate incidence rate ratios (IRR) and their 95% confidence intervals (CI).
After adjusting for potential confounders, the IRR for dementia was 1.53 (95% CI 0.77-3.03) among participants who had reported having prolonged or serious conflicts both with a supervisor and colleagues compared with participants who had never had such conflicts. In separate analyses stratified by sex, the IRRs were 2.14 (95% Cl 0.97-4.71) for men and 0.98 (95% Cl 0.29-3.32) for women.
Our findings did not support an overall association between experiencing prolonged or serious conflicts at work and incident dementia. However, because of the large differences in the point estimates for men and women, future research could aim at investigating potential sex differences regarding the association between conflicts at work and dementia.
仅有少数研究调查了社会关系的负面方面对认知功能的影响,且这些研究结果不一。工作中的冲突是社会关系负面方面的一部分,但工作中经历冲突作为痴呆症的风险因素尚未得到研究。因此,我们调查了与主管或同事长期或严重的工作冲突是否与老年时发生痴呆有关。
我们分析了来自哥本哈根城市心脏研究第三次调查的 6436 名男性和女性的数据。在 1991-1994 年的基线调查中,参与者报告了他们是否在工作中曾经历过长期或严重的冲突。参与者随访至 2014 年。我们使用泊松回归来估计发病率比(IRR)及其 95%置信区间(CI)。
在调整了潜在混杂因素后,与从未经历过此类冲突的参与者相比,报告与主管和同事都曾经历过长期或严重冲突的参与者发生痴呆的 IRR 为 1.53(95%CI 0.77-3.03)。在按性别分层的单独分析中,男性的 IRR 为 2.14(95%Cl 0.97-4.71),女性的 IRR 为 0.98(95%Cl 0.29-3.32)。
我们的研究结果不支持工作中经历长期或严重冲突与发生痴呆之间的总体关联。然而,由于男性和女性的点估计值存在较大差异,未来的研究可以针对工作冲突与痴呆之间的关联进行潜在的性别差异调查。