美托洛尔与比索洛尔对心血管疾病患者血脂和血糖谱影响的比较
Comparison of the Effects of Metoprolol and Bisoprolol on Lipid and Glucose Profiles in Cardiovascular Patients.
作者信息
Almeman Ahmad Abdulrahman, Beshir Yasir Ahmed, Aldosary Ahmad Hamad
机构信息
Clinical Pharmacology and Therapeutics Department, Qassim University, Buraydah, Qassim, Saudi Arabia.
Interventional Cardiology Department, Prince Sultan Cardiac Center, Buraydah, Qassim, Saudi Arabia.
出版信息
Curr Drug Saf. 2019;14(1):27-30. doi: 10.2174/1574886313666181029101247.
BACKGROUND
Cardioselective beta-blockers may affect glucose or lipid profiles.
OBJECTIVE
We sought to compare the effects of two beta-blockers, metoprolol and bisoprolol, as the most commonly used drugs in cardiology, on glucose and lipid profiles in patients with cardiovascular diseases.
METHODS
We conducted a retrospective cross-sectional matched study at Prince Sultan Cardiac Center in Burydah in August 2017. Patient records were screened, and adult patients with cardiovascular disorders who were treated with a stable dose of metoprolol or bisoprolol were included. Parameters related to glucose and lipid metabolism were compared using the Student's t-test between the two groups.
RESULTS AND CONCLUSION
The metoprolol and bisoprolol arms included 204 and 200 patients, respectively.
背景
心脏选择性β受体阻滞剂可能会影响血糖或血脂水平。
目的
我们试图比较两种β受体阻滞剂，美托洛尔和比索洛尔（心脏病学中最常用的药物）对心血管疾病患者血糖和血脂水平的影响。
方法
2017年8月，我们在布赖代的苏丹王子心脏中心进行了一项回顾性横断面匹配研究。对患者记录进行筛查，纳入接受稳定剂量美托洛尔或比索洛尔治疗的成年心血管疾病患者。使用学生t检验比较两组之间与葡萄糖和脂质代谢相关的参数。
结果与结论
美托洛尔组和比索洛尔组分别包括204例和200例患者。
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