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眼睑默克尔细胞癌病例系列:一种常被误诊的罕见疾病。

A case series of Merkel cell carcinoma of the eyelid: a rare entity often misdiagnosed.

作者信息

Iuliano Adriana, Tranfa Fausto, Clemente Lidia, Fossataro Federica, Strianese Diego

机构信息

Department of Neurosciences, Reproductive Sciences and Dentistry, University of Naples Federico II , Naples , Italy.

出版信息

Orbit. 2019 Oct;38(5):395-400. doi: 10.1080/01676830.2018.1537291. Epub 2018 Oct 29.

Abstract

Merkel cell carcinoma (MCC) is one of the rarest eyelid tumors, with high mortality rate due to lymphatic and metastatic spread. We hereby report six cases of patients with histological diagnosis of MCC referred to our Orbit Unit between 2012 and 2018, focusing on diagnosis, treatment, and subsequent follow up. All patients underwent surgical excision and systemic work-up. Both MCC TNM and eyelid MCC TNM were used to stage lesions. MCC of the eyelid is usually misdiagnosed as benign or other malignant lesions. A prompt examination and a wide local excision are mandatory. A close follow-up of these patients is advised due to high recurrence rate and lymphatic spread.

摘要

默克尔细胞癌(MCC)是最罕见的眼睑肿瘤之一,因其通过淋巴和转移扩散导致死亡率很高。我们在此报告2012年至2018年间转诊至我们眼眶科的6例经组织学诊断为MCC的患者,重点关注诊断、治疗及后续随访情况。所有患者均接受了手术切除和全身检查。采用MCC的TNM分期及眼睑MCC的TNM分期对病变进行分期。眼睑MCC通常被误诊为良性或其他恶性病变。必须进行快速检查并进行广泛局部切除。鉴于其高复发率和淋巴转移,建议对这些患者进行密切随访。

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