Schmitt W, Ramp U
Universitätsklinikum Düsseldorf, Klinik für Kiefer- und Plastische Gesichtschirurgie, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Mund Kiefer Gesichtschir. 2006 Nov;10(6):419-22. doi: 10.1007/s10006-006-0027-3.
Merkel cell carcinoma (MCC) of the skin is a rare form of cutaneous malignancy of neuroendocrine origin with a propensity to form cutaneous and lymphogenous metastases. The tumor, affecting predominately elderly patients, has a significantly higher incidence in female patients (80%) compared to male patients (20%). The mainstay of therapy is surgical resection with possible adjuvant radio- or chemotherapy.
A case of a 78-year-old patient with a MCC of the upper lid without lymph node involvement or distant metastasis is described. The tumor was resected and the defect closed by a temporal skin flap performing a temporary cantholysis. The clinical follow-up revealed an undisturbed eye lid function without any clinical or radiological signs of a locoregional or distant recurrence.
皮肤默克尔细胞癌（MCC）是一种罕见的神经内分泌源性皮肤恶性肿瘤，易于形成皮肤和淋巴转移。该肿瘤主要影响老年患者，女性患者（80%）的发病率明显高于男性患者（20%）。治疗的主要方法是手术切除，并可能辅以放疗或化疗。
描述了一例78岁上睑MCC患者，无淋巴结受累或远处转移。肿瘤被切除，缺损通过颞部皮瓣修复，并进行了临时眦切开术。临床随访显示眼睑功能未受影响，没有局部或远处复发的任何临床或放射学迹象。
