Talei Abdolrasoul, Tahmasebi Sedigheh, Akrami Majid, Zangouri Vahid, Rezaianzadeh Abbas, Arasteh Peyman, Eghbali Tannaz, Hosseini Sara
Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Surgical Oncology Division, General Surgery Department, Shiraz University of Medical Sciences, Shiraz, Iran.
Per Med. 2018 Nov;15(6):471-479. doi: 10.2217/pme-2018-0047. Epub 2018 Oct 30.
This is a description of the largest breast cancer (BC) registry in Iran, termed the Shiraz Breast Cancer Registry (SBCR).
Data on baseline and clinical characteristics, socioeconomic status, imaging, physical examination, histopathology, treatment and prognosis have been recorded for each individual.
Overall, 5937 were included in the report. Mean age of first presentation was 49.05 ± 11.69 years. Mean tumor size was 2.78 ± 1.76 cm. Most patients had stage 2 (46.9%) and 3 (25.5%) BCs, respectively. Most common type of BC was invasive ductal carcinoma (83.3%), followed by medullary carcinoma (3.8%). Overall, 12.9% were triple negative (HER2-, ER- and PR-).
The study provides an overview on the status of BC's in Iran and a wide opportunity for future studies.
本文描述了伊朗最大的乳腺癌登记处,即设拉子乳腺癌登记处(SBCR)。
记录了每个个体的基线和临床特征、社会经济状况、影像学检查、体格检查、组织病理学、治疗及预后等数据。
该报告共纳入5937例患者。首次就诊的平均年龄为49.05±11.69岁。平均肿瘤大小为2.78±1.76厘米。大多数患者分别处于乳腺癌2期(46.9%)和3期(25.5%)。最常见的乳腺癌类型是浸润性导管癌(83.3%),其次是髓样癌(3.8%)。总体而言,12.9%为三阴性(HER2阴性、雌激素受体阴性和孕激素受体阴性)。
该研究概述了伊朗乳腺癌的现状,并为未来研究提供了广泛机会。