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一项选择实验,旨在确定成功的癌症筛查项目的最重要元素,这些元素是根据那些研究和管理此类项目的人确定的。

A choice experiment to identify the most important elements of a successful cancer screening program according to those who research and manage such programs.

机构信息

London School of Hygiene and Tropical Medicine, London, UK.

Syreon Research Institute, Budapest, Hungary.

出版信息

Int J Health Plann Manage. 2019 Jan;34(1):e34-e45. doi: 10.1002/hpm.2697. Epub 2018 Oct 31.

Abstract

PURPOSE

The relationship between cancer screening activities in Europe and the health systems in which they are embedded varies, with some screening programs organized largely separately and others using existing health service staff and facilities. Whatever the precise arrangements, the opportunity for screening to achieve health gain depends on many elements interacting within and beyond the health system, from an accurate register identifying the target population to a means to ensure and monitor follow-up.

METHOD

A conjoint analysis was undertaken with 66 cancer screening experts from 31 countries taking part in EU-TOPIA (towards improved screening for breast, cervical and colorectal cancer in all of Europe) to identify priorities for an effective screening program, taking a whole system perspective. Ten attributes, each with two levels, were derived from a review of the literature and consultation with experts in cancer screening. Statistical software generated 12 profiles that were ranked by respondents and analyzed using standard conjoint analysis.

FINDINGS AND CONCLUSION

The most important attributes were having up-to-date and evidence-based guidelines, followed by mechanisms for systematic monitoring of screening uptake, having a population register covering all of the eligible population and monitoring long-term outcomes. In discussions about the results, participants argued that quality assurance and adherence to guidelines were important, even though they generated low scores in the experiment. This difference may be due some attributes being interrelated, more wide-ranging or the sequential nature of establishing an effective screening program, with guidelines being the first stage of the process.

摘要

目的

欧洲各地的癌症筛查活动与所嵌入的卫生系统之间存在着各种关系,一些筛查项目主要是独立组织的,而另一些则利用现有的卫生服务人员和设施。无论确切的安排如何,筛查实现健康收益的机会取决于卫生系统内外许多相互作用的因素,从准确识别目标人群的登记册到确保和监测后续行动的手段。

方法

来自 31 个国家的 66 名癌症筛查专家参与了欧盟-TOPIA(改善全欧洲乳腺癌、宫颈癌和结直肠癌筛查),采用联合分析方法,从文献回顾和与癌症筛查专家协商中得出了 10 个具有两个水平的属性,从整体系统的角度确定了有效筛查计划的优先事项。统计软件生成了 12 个由受访者排名的配置文件,并使用标准联合分析进行了分析。

结果和结论

最重要的属性是拥有最新和基于证据的指南,其次是系统监测筛查参与率的机制、拥有涵盖所有合格人群的人口登记册以及监测长期结果。在讨论结果时,参与者认为质量保证和遵守指南很重要,即使它们在实验中得分较低。这种差异可能是由于某些属性相互关联、更广泛或建立有效筛查计划的顺序性质,指南是该过程的第一阶段。

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