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More than one DNA sequence encodes the 2''-O-adenylyltransferase phenotype.

作者信息

Lee S C, Cleary P P, Gerding D N

出版信息

Antimicrob Agents Chemother. 1987 Apr;31(4):667-70. doi: 10.1128/AAC.31.4.667.

DOI:10.1128/AAC.31.4.667
PMID:3038004
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC174806/
Abstract

Biochemical and phenotypic assays indicate that three enterobacterial R plasmids isolated in a single hospital encode 2''-O-adenylyltransferase [ANT(2'')], and an ANT(2'')-specific probe was developed from one plasmid. Southern hybridization revealed the three plasmids to be unrelated and, further, showed their ANT(2'')-encoding genes to be different.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4483/174806/f70fc30edbea/aac00095-0217-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4483/174806/efa03ef8e543/aac00095-0217-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4483/174806/f70fc30edbea/aac00095-0217-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4483/174806/efa03ef8e543/aac00095-0217-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4483/174806/f70fc30edbea/aac00095-0217-b.jpg

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本文引用的文献

1
Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature.根据热变性温度确定脱氧核糖核酸的碱基组成
J Mol Biol. 1962 Jul;5:109-18. doi: 10.1016/s0022-2836(62)80066-7.
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R-factor mediated gentamicin resistance: A new enzyme which modifies aminoglycoside antibiotics.R 因子介导的庆大霉素耐药性：一种修饰氨基糖苷类抗生素的新酶。
FEBS Lett. 1971 May 20;14(5):293-296. doi: 10.1016/0014-5793(71)80282-x.
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Analysis of gene control signals by DNA fusion and cloning in Escherichia coli.通过在大肠杆菌中进行DNA融合和克隆分析基因控制信号。
质粒图谱在疾病暴发的流行病学监测及追踪抗生素耐药性传播中的应用。
Clin Microbiol Rev. 1988 Apr;1(2):228-43. doi: 10.1128/CMR.1.2.228.
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Correlation between aminoglycoside resistance profiles and DNA hybridization of clinical isolates.临床分离株氨基糖苷类耐药谱与DNA杂交之间的相关性
Antimicrob Agents Chemother. 1991 Nov;35(11):2253-61. doi: 10.1128/AAC.35.11.2253.
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Plasmid macroevolution in a nosocomial environment: demonstration of a persistent molecular polymorphism and construction of a cladistic phylogeny on the basis of restriction data.
Mol Gen Genet. 1984;194(1-2):173-8. doi: 10.1007/BF00383513.
5
New plasmid-mediated aminoglycoside adenylyltransferase of broad substrate range that adenylylates amikacin.新的质粒介导的具有广泛底物范围的氨基糖苷腺苷酸转移酶，该酶可使阿米卡星腺苷酸化。
Antimicrob Agents Chemother. 1981 Jul;20(1):75-80. doi: 10.1128/AAC.20.1.75.
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A system for shotgun DNA sequencing.一种用于鸟枪法DNA测序的系统。
Nucleic Acids Res. 1981 Jan 24;9(2):309-21. doi: 10.1093/nar/9.2.309.
7
Development of a DNA probe for the structural gene of the 2"-O-adenyltransferase aminoglycoside-modifying enzyme.用于2”-O-腺苷基转移酶氨基糖苷修饰酶结构基因的DNA探针的研制。
J Infect Dis. 1984 Nov;150(5):678-87. doi: 10.1093/infdis/150.5.678.
8
Pedigrees of some mutant strains of Escherichia coli K-12.大肠杆菌K-12某些突变菌株的谱系。
Bacteriol Rev. 1972 Dec;36(4):525-57. doi: 10.1128/br.36.4.525-557.1972.
9
Comparison of aminoglycoside resistance patterns in Japan, Formosa, and Korea, Chile, and the United States.日本、台湾、韩国、智利和美国氨基糖苷类耐药模式的比较。 需说明的是，台湾是中国的省级行政区，不是一个国家，应使用正确的表述来维护国家领土完整和主权统一。
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10
Hospital distribution, persistence, and reintroduction of related gentamicin R plasmids.相关庆大霉素R质粒在医院内的分布、持续性及再引入
Antimicrob Agents Chemother. 1986 Apr;29(4):654-9. doi: 10.1128/AAC.29.4.654.