MMWR Morb Mortal Wkly Rep. 2018 Nov 2;67(43):1208-1210. doi: 10.15585/mmwr.mm6743a3.
During 2017, CDC received 1,521 reports of acute hepatitis A virus (HAV) infections from California, Kentucky, Michigan, and Utah; the majority of infections were among persons reporting injection or noninjection drug use or homelessness. Investigations conducted by local and state health departments indicated that direct person-to-person transmission of HAV infections was occurring, differing from other recent, large HAV outbreaks attributed to consumption of contaminated commercial food products. Outbreaks with direct HAV transmission among persons reporting drug use or homelessness signals a shift in HAV infection epidemiology in the United States, and vaccination of these populations at high risk can prevent future outbreaks.
2017 年,疾病预防控制中心收到加利福尼亚州、肯塔基州、密歇根州和犹他州 1521 例急性甲型肝炎病毒(HAV)感染报告;大多数感染者报告有注射或非注射吸毒或无家可归史。地方和州卫生部门进行的调查表明,HAV 感染正在发生直接的人际传播,与其他最近发生的、因食用受污染的商业食品而导致的大规模 HAV 暴发不同。在报告有吸毒或无家可归史的人群中发生的 HAV 直接传播暴发表明,美国的 HAV 感染流行病学正在发生转变,对这些高危人群进行疫苗接种可以预防未来的暴发。