等位基因特异性表达阐明了顺式调控逻辑。 - Suppr

Suppr

超能文献

Allele-specific expression elucidates cis-regulatory logic.

作者信息

Delbare Sofie Y N, Clark Andrew G

机构信息

Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America.

出版信息

PLoS Genet. 2018 Nov 1;14(11):e1007690. doi: 10.1371/journal.pgen.1007690. eCollection 2018 Nov.

DOI:10.1371/journal.pgen.1007690

PMID:30383744

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6211629/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a68/6211629/ec8aef44bad4/pgen.1007690.g001.jpg

相似文献

Allele-specific expression elucidates cis-regulatory logic.等位基因特异性表达阐明了顺式调控逻辑。

PLoS Genet. 2018 Nov 1;14(11):e1007690. doi: 10.1371/journal.pgen.1007690. eCollection 2018 Nov.

Compensatory cis-trans evolution and the dysregulation of gene expression in interspecific hybrids of Drosophila.果蝇种间杂种中的补偿性顺反进化与基因表达失调

Genetics. 2005 Dec;171(4):1813-22. doi: 10.1534/genetics.105.047449. Epub 2005 Sep 2.

Allele-specific KRT1 expression is a complex trait.等位基因特异性角蛋白1表达是一种复杂性状。

PLoS Genet. 2006 Jun;2(6):e93. doi: 10.1371/journal.pgen.0020093. Epub 2006 Jun 9.

Transvection in Drosophila: trans-interaction between yellow enhancers and promoter is strongly suppressed by a cis-promoter only in certain genomic regions.果蝇中的转位作用：黄色增强子与启动子之间的反式相互作用仅在某些基因组区域被顺式启动子强烈抑制。

Chromosoma. 2017 Jun;126(3):431-441. doi: 10.1007/s00412-016-0605-6. Epub 2016 Jun 14.

Logic functions of the genomic cis-regulatory code.基因组顺式调控编码的逻辑功能。

Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):4954-9. doi: 10.1073/pnas.0409624102. Epub 2005 Mar 23.

Characterization of the cis elements in the proximal promoter regions of the anthocyanin pathway genes reveals a common regulatory logic that governs pathway regulation.花青素途径基因近端启动子区域顺式元件的表征揭示了一种控制途径调控的共同调控逻辑。

J Exp Bot. 2015 Jul;66(13):3775-89. doi: 10.1093/jxb/erv173. Epub 2015 Apr 23.

Buffering of Genetic Regulatory Networks in Drosophila melanogaster.黑腹果蝇遗传调控网络的缓冲作用

Genetics. 2016 Jul;203(3):1177-90. doi: 10.1534/genetics.116.188797. Epub 2016 May 18.

Evolutionary changes in cis and trans gene regulation.顺式和反式基因调控中的进化变化。

Nature. 2004 Jul 1;430(6995):85-8. doi: 10.1038/nature02698.

Regulatory changes underlying expression differences within and between Drosophila species.果蝇物种内部和物种之间表达差异背后的调控变化。

Nat Genet. 2008 Mar;40(3):346-50. doi: 10.1038/ng.77. Epub 2008 Feb 17.

cis-Acting sequences controlling the adult-specific transcription pattern of the Drosophila affinidisjuncta Adh gene.控制果蝇affinidisjuncta Adh基因成虫特异性转录模式的顺式作用序列。

Dev Genet. 1998;23(2):119-27. doi: 10.1002/(SICI)1520-6408(1998)23:2<119::AID-DVG4>3.0.CO;2-9.

引用本文的文献

A multi-tissue atlas of allelic-specific expression reveals the characteristics, mechanisms, and relationship with dominant effects in cattle.一份等位基因特异性表达的多组织图谱揭示了牛的特征、机制以及与显性效应的关系。

BMC Biol. 2025 May 30;23(1):148. doi: 10.1186/s12915-025-02257-0.

Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma.利用等位基因特异性表达进行胶质母细胞瘤治疗反应基因的发现。

Cancer Res. 2022 Feb 1;82(3):377-390. doi: 10.1158/0008-5472.CAN-21-0810. Epub 2021 Dec 13.

Contributions of cis- and trans-Regulatory Evolution to Transcriptomic Divergence across Populations in the Drosophila mojavensis Larval Brain.顺式和反式调控进化对果蝇幼虫大脑中不同种群转录组差异的贡献。

Genome Biol Evol. 2020 Aug 1;12(8):1407-1418. doi: 10.1093/gbe/evaa145.

本文引用的文献

Spatially varying cis-regulatory divergence in Drosophila embryos elucidates cis-regulatory logic.果蝇胚胎中空间变化的顺式调控分歧阐明了顺式调控逻辑。

PLoS Genet. 2018 Nov 1;14(11):e1007631. doi: 10.1371/journal.pgen.1007631. eCollection 2018 Nov.

Landscape of X chromosome inactivation across human tissues.人类组织中X染色体失活的全景图。

Nature. 2017 Oct 11;550(7675):244-248. doi: 10.1038/nature24265.

The embryo at single-cell transcriptome resolution.单细胞转录组分辨率下的胚胎。

Science. 2017 Oct 13;358(6360):194-199. doi: 10.1126/science.aan3235. Epub 2017 Aug 31.

Comprehensive single-cell transcriptional profiling of a multicellular organism.多细胞生物的全面单细胞转录谱分析。

Science. 2017 Aug 18;357(6352):661-667. doi: 10.1126/science.aam8940.

The time-resolved transcriptome of C. elegans.秀丽隐杆线虫的时间分辨转录组

Genome Res. 2016 Oct;26(10):1441-1450. doi: 10.1101/gr.202663.115. Epub 2016 Aug 16.

Visualization and analysis of gene expression in tissue sections by spatial transcriptomics.空间转录组学在组织切片中基因表达的可视化和分析。

Science. 2016 Jul 1;353(6294):78-82. doi: 10.1126/science.aaf2403.

Isolation of specific neurons from C. elegans larvae for gene expression profiling.从秀丽隐杆线虫幼虫中分离特定神经元用于基因表达谱分析。

PLoS One. 2014 Nov 5;9(11):e112102. doi: 10.1371/journal.pone.0112102. eCollection 2014.

Transcriptional enhancers: from properties to genome-wide predictions.转录增强子：从特性到全基因组预测。

Nat Rev Genet. 2014 Apr;15(4):272-86. doi: 10.1038/nrg3682. Epub 2014 Mar 11.

Tempo and mode of regulatory evolution in Drosophila.果蝇中调控进化的时空调控。

Genome Res. 2014 May;24(5):797-808. doi: 10.1101/gr.163014.113. Epub 2014 Feb 24.

Extensive divergence of transcription factor binding in Drosophila embryos with highly conserved gene expression.转录因子结合在果蝇胚胎中高度保守的基因表达中广泛分歧。

PLoS Genet. 2013;9(9):e1003748. doi: 10.1371/journal.pgen.1003748. Epub 2013 Sep 12.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验