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自发性高血压大鼠血管中血管紧张素转换酶活性对西拉普利反应的差异。

Difference in response of vascular angiotensin converting enzyme activity to cilazapril in SHR.

作者信息

Nakamura Y, Nakamura K, Nakamura K

出版信息

Clin Exp Hypertens A. 1987;9(2-3):351-5. doi: 10.3109/10641968709164195.

DOI:10.3109/10641968709164195
PMID:3038393
Abstract

Angiotensin I converting enzyme (ACE) activity was found in all rat arteries and veins examined, considerably varied among these vessels, and usually higher in arteries than in corresponding veins except for femoral and subclavian pairs. Decrease of vascular ACE activity in response to cilazapril at hypotensive doses varied in vessels and was not dependent on their ACE activity levels.

摘要

在所有被检测的大鼠动脉和静脉中均发现有血管紧张素I转换酶(ACE)活性,这些血管中的活性差异很大,除股动脉和锁骨下动脉外,通常动脉中的ACE活性高于相应静脉。在降压剂量下,西拉普利引起的血管ACE活性降低在不同血管中有所不同,且不依赖于其ACE活性水平。

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