Engel U, Bay V, Mier C
Chirurg. 1987 May;58(5):341-3.
This paper reports on 96 mediastinal tumors situated exclusively or mainly in the anterior mediastinum. Early surgical intervention is always indicated to establish the diagnosis and to ensure as radical a tumor resection as possible. The surgical approach depends on the tumor size and localization and is made either by sternotomy or thoracotomy. The prognosis depends on the histological classification of the tumors: out of 30 patients with lymphomas, 19 survived as compared to 10 out of 21 patients with thymoma and 15 out of 18 patients with mesenchymal tumors. Of 16 patients with endothoracic and retrosternal goiters, none died of a cause connected with the goiter and nine out of 11 patients with mesodermal tumors survived. The indication for surgery should be established extensively, since one third of the tumors is malignant and the surgical lethality (1.8%) is very low.
本文报告了96例仅位于或主要位于前纵隔的纵隔肿瘤。始终建议早期进行手术干预以明确诊断并确保尽可能彻底地切除肿瘤。手术方式取决于肿瘤的大小和位置，可通过胸骨切开术或开胸术进行。预后取决于肿瘤的组织学分类：30例淋巴瘤患者中有19例存活，21例胸腺瘤患者中有10例存活，18例间叶组织肿瘤患者中有15例存活。16例胸内和胸骨后甲状腺肿患者中，无一例因与甲状腺肿相关的原因死亡，11例中胚层肿瘤患者中有9例存活。手术指征应广泛确定，因为三分之一的肿瘤是恶性的，且手术死亡率（1.8%）非常低。
