Nakahara K, Fujii Y, Matsumura A, Mizuta T, Minami M, Inada K, Matsuda H
First Department of Surgery, Osaka University Medical School, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1995 Jun;43(6):825-30.
To elucidate the role of surgery for MMT, 214 patients during past 34 years were historically divided into the early (1960-1971, n = 80), intermediate (1972-1981, n = 79) and late series (1982-1993, n = 64). The thoracotomy rate for MMT, the rate of thoracotomy after preoperative diagnosis was done, and the number of postoperative survivors were significantly higher in the late series, compared with the early series. The intermediate series located between the early and late series. Nine patients in the late series undergoing chemo-radiation therapies obtained a good result after complete resection of the residual tissue. We conclude that surgical treatment of MMT should be based on accurate preoperative diagnosis and a distinct role for multidisciplinary treatment, especially regarding malignant thymoma, malignant lymphoma and malignant germ cell tumor.
为阐明手术在纵隔恶性肿瘤（MMT）治疗中的作用，回顾性分析了过去34年间的214例患者，并将其分为早期（1960 - 1971年，n = 80）、中期（1972 - 1981年，n = 79）和晚期组（1982 - 1993年，n = 64）。与早期组相比，晚期组MMT的开胸率、术前诊断后开胸率及术后存活人数均显著更高。中期组情况介于早期组和晚期组之间。晚期组中有9例接受放化疗的患者在残留组织完全切除后取得了良好疗效。我们得出结论，MMT的手术治疗应基于准确的术前诊断以及多学科治疗的明确作用，尤其是对于恶性胸腺瘤、恶性淋巴瘤和恶性生殖细胞肿瘤。
