Berlanga-Macías Carlos, Pozuelo-Carrascosa Diana P, Álvarez-Bueno Celia, Martínez-Hortelano Jose Alberto, Garrido-Miguel Miriam, Martínez-Vizcaíno Vicente
Health and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, Spain.
Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Talca, Chile.
BMJ Open. 2018 Oct 31;8(10):e023223. doi: 10.1136/bmjopen-2018-023223.
Breast feeding has been considered important due to its short-term and long-term benefits on infant and maternal health. Regarding the long-term benefits, the influence of exclusive breastfeeding on cardiorespiratory fitness (CRF) during childhood and adolescence has been studied, although with controversial conclusions. This study protocol aims to provide a clear and standardised procedure for systematically reviewing the relationship between breast feeding, in terms of duration and exclusivity, and CRF in children and adolescents.
This systematic review and meta-analysis protocol is reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols. A literature search will be conducted in MEDLINE, EMBASE, Web of Science and Cochrane Library. Observational studies regarding the association between breast feeding and CRF in children and adolescents written in English or Spanish will be included. A Critical Appraisal Checklist for Analytical Cross Sectional Studies and The Newcastle-Ottawa Quality Assessment Scale for longitudinal studies will be used for quality assessment of included studies. Standardised mean differences of CRF by exclusive breastfeeding categories will be calculated as the primary outcome. Subgroup analyses and meta-regression will be performed based on the sources of heterogeneity.
This evidence-based systematic review will summarise the relevant information on the association of exclusive breast feeding and CRF in children and adolescents. The results will be disseminated by publication in a peer-reviewed journal. Given that the data used for this systematic review will be exclusively extracted from published studies, ethical approval will not be required.
CRD42018082642.
母乳喂养因其对母婴健康的短期和长期益处而被视为重要。关于长期益处，已对纯母乳喂养对儿童期和青少年期心肺适能（CRF）的影响进行了研究，不过结论存在争议。本研究方案旨在提供一个清晰且标准化的程序，以系统评价母乳喂养在持续时间和排他性方面与儿童及青少年CRF之间的关系。
本系统评价和荟萃分析方案是按照系统评价与荟萃分析方案的首选报告项目进行报告的。将在MEDLINE、EMBASE、科学引文索引和考克兰图书馆进行文献检索。将纳入以英文或西班牙文撰写的关于儿童及青少年母乳喂养与CRF之间关联的观察性研究。将使用分析性横断面研究的批判性评价清单和纵向研究的纽卡斯尔 - 渥太华质量评估量表对纳入研究进行质量评估。将计算按纯母乳喂养类别划分的CRF标准化均数差值作为主要结局。将基于异质性来源进行亚组分析和荟萃回归。
这项基于证据的系统评价将总结关于儿童及青少年纯母乳喂养与CRF关联的相关信息。结果将通过在同行评审期刊上发表进行传播。鉴于本系统评价所使用的数据将仅从已发表的研究中提取，因此无需伦理批准。
CRD42018082642。
