Akbulut Sami, Isik Burak, Cicek Egemen, Samdanci Emine, Yilmaz Sezai
Department of Surgery and Liver Transplant Institute, Inonu University Faculty of Medicine, Malatya 44280, Turkey.
Department of Surgery, Inonu University Faculty of Medicine, Malatya 44280, Turkey.
World J Hepatol. 2018 Oct 27;10(10):780-784. doi: 10.4254/wjh.v10.i10.780.
To our best knowledge, no case of a tumor that was incidentally detected during living donor hepatectomy (LDH) has been reported in the English language medical literature. We present two cases in which grade I neuroendocrine tumors (NET) were incidentally detected during our twelve-year LDH experience. First Case: A 26-year-old male underwent LDH for his brother suffering from HBV-related chronic liver disease (CLD). After right lobe LDH, intestinal length was measured as part of a study concerning the relationship between small intestinal lengths and surgical procedure. At this stage, a mass lesion with a size of 10 mm × 10 mm was detected on the antimesenteric surface, approximately 90 cm proximal to the ileocecal valve. A wedge resection with primary intestinal anastomosis was performed. Second Case: A 29-year-old male underwent right lobe LDH for his father with hepatitis B virus (HBV)-related CLD. An abdominal exploration immediately prior to the closure of the incision revealed that the appendix vermiformis was edematous and had firmness with a size of 8-10 mm at its tip. An appendectomy was performed. The pathological examinations of the specimens of both patients revealed grade 1 NET. In conclusion, even if patients undergoing LDH are healthy individuals, whole abdominal cavity should be gently palpated and all findings recorded after completing laparotomy. Suspected masses or lesions should be confirmed by frozen section examination. Such an approach would avert potential medicolegal issues.
据我们所知,英文医学文献中尚未报道过在活体肝移植手术(LDH)期间偶然发现肿瘤的病例。我们报告两例在我们十二年的活体肝移植手术经验中偶然发现的I级神经内分泌肿瘤(NET)病例。第一例:一名26岁男性为其患有乙肝相关慢性肝病(CLD)的兄弟进行活体肝移植手术。右半肝活体肝移植术后,作为一项关于小肠长度与手术操作关系研究的一部分,测量了小肠长度。在此阶段,在距回盲瓣约90厘米的肠系膜对侧表面发现一个大小为10毫米×10毫米的肿块病变。进行了楔形切除并一期肠吻合。第二例:一名29岁男性为其患有乙肝病毒(HBV)相关慢性肝病的父亲进行右半肝活体肝移植手术。在切口即将缝合前进行腹部探查时发现阑尾水肿,其尖端质地硬,大小为8 - 10毫米。进行了阑尾切除术。两名患者标本的病理检查均显示为1级神经内分泌肿瘤。总之,即使接受活体肝移植手术的患者是健康个体,在完成剖腹手术后也应轻柔地触诊整个腹腔并记录所有发现。可疑肿块或病变应通过冰冻切片检查予以确认。这样的做法可以避免潜在的医疗法律问题。