Arduini D, Rizzo G, Parlati E, Dell'Acqua S, Romanini C, Mancuso S
Gynecol Obstet Invest. 1987;23(4):226-9. doi: 10.1159/000298865.
Fetal heart rate and fetal movements were recorded over a 24-hour interval in a totally adrenalectomized pregnant woman at term. Cortisol, ACTH, unconjugated estriol and 17 beta-estradiol were contemporaneously measured every 2 h in the maternal peripheral plasma. Owing to the substitution therapy the patient showed a loss of circadian variations of all the hormones investigated. Moreover, the circadian rhythms of fetal heart rate and fetal movements, usually present at term, were no longer evident. We can thus suggest that the circadian variations of plasma maternal cortisol could affect the alternations of fetal behaviour.
对一名足月妊娠的完全肾上腺切除的孕妇进行了24小时的胎儿心率和胎动记录。每2小时同时测定母体外周血浆中的皮质醇、促肾上腺皮质激素、未结合雌三醇和17β-雌二醇。由于替代疗法，患者所检测的所有激素均失去了昼夜变化规律。此外，足月时通常会出现的胎儿心率和胎动的昼夜节律也不再明显。因此我们可以认为，母体血浆皮质醇的昼夜变化可能会影响胎儿行为的交替。
