Lunshof S, Boer K, Wolf H, van Hoffen G, Bayram N, Mirmiran M
Academic Medical Center, Department of Obstetrics and Gynaecology, Amsterdam, The Netherlands.
Am J Obstet Gynecol. 1998 Feb;178(2):247-54. doi: 10.1016/s0002-9378(98)80008-2.
We quantified the presence of diurnal rhythms in various computerized fetal heart rate parameters in normal pregnancies to assess their clinical relevance.
Modified cosine analysis was applied to the outcomes of computerized analysis of continuous 24-hour fetal heart rate recordings in 26 normal pregnancies. Diurnal rhythms in maternal heart rate and plasma hormones were assessed in 15 and 17 pregnancies, respectively. Correlations between maternal and fetal rhythms were calculated.
A significant diurnal rhythm in basal heart rate was present in 73% of the fetuses and was closely related to the maternal heart rate rhythm. Diurnal rhythms in heart rate variability, accelerations, and activity were present in only 30% to 50% of the fetuses.
The mother entrains fetal diurnal rhythms. The normal variability in neural development may account for the absence of diurnal rhythms in some fetuses.
我们对正常妊娠中各种计算机化胎儿心率参数的昼夜节律存在情况进行量化，以评估其临床相关性。
对26例正常妊娠的连续24小时胎儿心率记录进行计算机化分析的结果应用修正余弦分析。分别在15例和17例妊娠中评估母体心率和血浆激素的昼夜节律。计算母体和胎儿节律之间的相关性。
73%的胎儿基础心率存在显著的昼夜节律，且与母体心率节律密切相关。仅30%至50%的胎儿心率变异性、加速和活动存在昼夜节律。
母亲带动胎儿的昼夜节律。神经发育的正常变异性可能解释了一些胎儿不存在昼夜节律的原因。
