Doggett Betty M, Session-Augustine Nellie, Roig Joseph, Strunk Matthew, Valiyaparambil Shiney, Sarode Ravi, De Simone Nicole
Division of Transfusion Medicine and Hemostasis, Department of Pathology, UT Southwestern Medical Center, Dallas, Texas.
Therapeutic Apheresis and Cellular Therapy, Terumo BCT, Lakewood, Colorado.
J Clin Apher. 2019 Feb;34(1):21-25. doi: 10.1002/jca.21665. Epub 2018 Nov 2.
Apheresis treatments, which involve the removal of a component of blood, generally require one access and one return line to continuously draw and return blood into the extracorporeal circuit. At our center, we prefer to use peripheral venous access to avoid central line-related complications, especially infection. Motivated by patient-centered care, the single-needle (SN) option for therapeutic plasma exchange (TPE) offered on the Spectra Optia (Terumo BCT, Lakewood, CO) was evaluated. Five patients underwent procedures using both SN and dual-needle (DN) plasma exchange procedures using the Spectra Optia. TPE procedures ran a median of 51 (range:10-102) minutes longer using the SN-TPE option. Inlet flow rates, plasma removal efficiency, and incidence of citrate reactions were similar between SN- and DN-procedures. Patients reported great satisfaction with SN-TPE.
血液成分分离治疗涉及去除血液中的一种成分，通常需要一根进液管和一根回液管，以便持续将血液抽出并回输到体外循环中。在我们中心，我们更倾向于使用外周静脉通路，以避免与中心静脉导管相关的并发症，尤其是感染。出于以患者为中心的护理理念，我们对Spectra Optia（Terumo BCT公司，科罗拉多州莱克伍德市）提供的单针（SN）治疗性血浆置换（TPE）方案进行了评估。5例患者分别接受了使用Spectra Optia的SN和双针（DN）血浆置换操作。使用SN-TPE方案进行TPE操作的时间中位数比使用DN-TPE方案长51分钟（范围：10 - 102分钟）。SN和DN操作之间的入口流速、血浆去除效率以及枸橼酸盐反应发生率相似。患者对SN-TPE非常满意。
