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将光学相干断层扫描纳入白内障术前设备中:是额外的需要还是额外的负担?

Incorporating Optical Coherence Tomography in the Cataract Preoperative Armamentarium: Additional Need or Additional Burden?

机构信息

Raghudeep Eye Hospital, Iladevi Cataract Centre, Ahmedabad, India.

Raghudeep Eye Hospital, Iladevi Cataract Centre, Ahmedabad, India.

出版信息

Am J Ophthalmol. 2019 Feb;198:209-214. doi: 10.1016/j.ajo.2018.10.025. Epub 2018 Oct 31.

DOI:10.1016/j.ajo.2018.10.025
PMID:30389372
Abstract

PURPOSE

To determine the usefulness of preoperative optical coherence tomography (OCT) examination to detect asymptomatic macular abnormalities in patients scheduled for cataract surgery.

METHODS

Design: Prospective, interventional case series.

SETTING

Iladevi Cataract and Visakha Eye Center, Ahmedabad, India.

STUDY POPULATION

Patients undergoing cataract surgery and intraocular lens (IOL) implantation for senile cataracts. Preoperatively no retinal/macular pathology was identified on clinical evaluation.

INTERVENTION

All eyes underwent macular 5-line raster evaluation using spectral-domain OCT before and after cataract surgery (monthly for 3 months). Central subfield thickness (CST) analysis was done.

OUTCOME MEASURES

The primary outcome measure was determining the incidence of asymptomatic retinal lesions on OCT examination in clinically "normal" maculas. Secondary outcome measures included documenting change in corrected distance visual acuity and OCT thickness postoperatively.

RESULTS

A total of 1444 eyes were evaluated. OCT revealed asymptomatic lesions in 133 (9.21%) patients. At 3 months, all eyes showed significant median visual improvement (from 0.45 ± 0.13 logMAR to 0.06 ± 0.08 logMAR; P = .015) and insignificant median CST change (from 223.34 ± 21.1 μm to 249.12 ± 19.24 μm; P = .19). One eye showed increased vitreomacular traction (3 months). Patients with asymptomatic lesions did not have significantly worse postoperative visual outcomes at 3 months (from 0.52 ± 0.16 logMAR to 0.14 ± 0.1 logMAR; P = .12).

CONCLUSION

A total of 9.21% patients with clinically normal maculas had subtle pathology detected on OCT, but this subset of patients did not have worse postoperative visual outcomes compared to eyes with normal OCT scans. Thus, a careful pre-cataract surgery fundus examination remains an essential part of the presurgical patient evaluation.

摘要

目的

确定术前光学相干断层扫描(OCT)检查在检测计划接受白内障手术的患者无症状性黄斑异常方面的作用。

方法

设计:前瞻性、干预性病例系列研究。

地点

印度艾哈迈达巴德的 Iladevi 白内障和 Visakha 眼科中心。

研究人群

接受白内障手术和人工晶状体(IOL)植入治疗老年性白内障的患者。术前临床评估未发现视网膜/黄斑病变。

干预

所有患者均在白内障手术后(每月 1 次,持续 3 个月)进行黄斑 5 线光栅评估,并使用频域 OCT。进行中央视网膜厚度(CST)分析。

主要结局测量指标

确定临床“正常”黄斑的 OCT 检查中无症状性视网膜病变的发生率。次要结局测量指标包括记录术后矫正视力和 OCT 厚度的变化。

结果

共评估了 1444 只眼。OCT 在 133 例(9.21%)患者中发现无症状性病变。3 个月时,所有眼均显示出显著的中位视力改善(从 0.45 ± 0.13 logMAR 改善至 0.06 ± 0.08 logMAR;P=0.015)和不显著的 CST 中位变化(从 223.34 ± 21.1 μm 增加至 249.12 ± 19.24 μm;P=0.19)。1 只眼出现玻璃体黄斑牵引增加(3 个月)。无症状病变患者在 3 个月时的术后视力结局无显著差异(从 0.52 ± 0.16 logMAR 改善至 0.14 ± 0.1 logMAR;P=0.12)。

结论

在临床正常黄斑的患者中,有 9.21%的患者在 OCT 上发现了细微的病变,但这部分患者与 OCT 扫描正常的患者相比,术后视力结局并没有更差。因此,在白内障手术前进行仔细的眼底检查仍然是术前患者评估的重要组成部分。

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