开发有意义的针对癌症的联合免疫疗法。
Developing combination immunotherapies against cancer that make sense.
机构信息
Laboratory of Molecular Oncology, Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Québec H2W1R7, Canada.
Department of Medicine, University of Montréal, Montréal, Québec H3C3J7, Canada.
出版信息
Sci Immunol. 2018 Nov 2;3(29). doi: 10.1126/sciimmunol.aav1872.
PMID:30389799
Abstract
Mechanistic preclinical studies provide a compelling case that combination immunotherapies that target the receptors PD-1 and GITR may demonstrate synergy in human cancer.
摘要
机制性临床前研究提供了一个令人信服的案例，表明针对 PD-1 和 GITR 受体的联合免疫疗法可能在人类癌症中表现出协同作用。
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