Klaeboe Lars Gunnar, Edvardsen Thor
Department of Cardiology and Center for Cardiological Innovation, Oslo University Hospital, Rikshospitalet, PO Box 4950, 0424, Oslo, Norway.
Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
J Echocardiogr. 2019 Mar;17(1):10-16. doi: 10.1007/s12574-018-0405-5. Epub 2018 Nov 2.
Left ventricular (LV) ejection fraction (LVEF) is the most validated and commonly used echocardiographic measure of systolic function. LVEF has a unique position in cardiology having severed as selection criteria for therapeutic trials that constitute the evidence base of today's treatment recommendations. Assessment of LV systolic function by global longitudinal strain (GLS) from speckle tracking echocardiography (STE) is a sensitive and feasible method that overcomes many of the limitations of LVEF, including reproducibility issues of serial testing and detection of LV dysfunction in pathologically remodeled hearts. This review discusses the role of STE as a complementary method to LVEF in estimation of LV systolic function.
左心室射血分数（LVEF）是用于评估收缩功能的、最具认可度且最常用的超声心动图测量指标。LVEF在心脏病学领域占据独特地位，它一直是构成当今治疗建议证据基础的治疗试验的选择标准。通过斑点追踪超声心动图（STE）的整体纵向应变（GLS）评估左心室收缩功能是一种敏感且可行的方法，它克服了LVEF的许多局限性，包括连续检测的可重复性问题以及病理重塑心脏中左心室功能障碍的检测问题。本文综述讨论了STE作为LVEF的补充方法在评估左心室收缩功能中的作用。
