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前庭神经鞘瘤(包括神经纤维瘤病2型)的管理:面神经相关考量

Management of Vestibular Schwannoma (Including NF2): Facial Nerve Considerations.

作者信息

Kaul Vivian, Cosetti Maura K

机构信息

Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York Eye and Ear of Mount Sinai, Floor 6, 310 East 14th Street, New York, NY 10003, USA.

Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York Eye and Ear of Mount Sinai, Floor 6, 310 East 14th Street, New York, NY 10003, USA.

出版信息

Otolaryngol Clin North Am. 2018 Dec;51(6):1193-1212. doi: 10.1016/j.otc.2018.07.015.

DOI:10.1016/j.otc.2018.07.015
PMID:30390772
Abstract

Current consensus on optimal treatment of vestibular schwannoma remains poorly established; treatment options include observation, stereotactic radiosurgery, microsurgical resection, medical therapy, or a combination of these. Treatment should be individualized and incorporate the multitude of patient- and tumor-specific characteristics known to affect outcome. Treatment paradigms for sporadic and neurofibromatosis type 2-related tumors are distinct and decision-making in neurofibromatosis type 2 is uniquely challenging. In all cases, treatment should maximize tumor control and minimize functional deficit.

摘要

目前关于前庭神经鞘瘤最佳治疗方法的共识仍不明确;治疗选择包括观察、立体定向放射外科、显微手术切除、药物治疗或这些方法的联合应用。治疗应个体化,并综合考虑已知会影响治疗结果的众多患者和肿瘤特异性特征。散发性肿瘤和2型神经纤维瘤病相关肿瘤的治疗模式不同,2型神经纤维瘤病的决策具有独特的挑战性。在所有情况下,治疗都应最大限度地控制肿瘤并尽量减少功能缺陷。

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