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神经内镜辅助显微镜治疗大型(库斯四级)前庭神经鞘瘤的疗效分析

Analysis of the effect of neuroendoscopy-assisted microscopy in the treatment of Large (Koos grade IV) vestibular schwannoma.

作者信息

Yang Zhenxing, Xiong Xiaoxing, Jian Zhihong, Du Li

机构信息

Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.

Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.

出版信息

Front Oncol. 2023 Jan 17;13:1033954. doi: 10.3389/fonc.2023.1033954. eCollection 2023.

Abstract

INTRODUCTION

This article aimed to investigate the effects of the endoscopic-assisted microsurgery technique on the resection of large (Koos grade IV) vestibular schwannoma (VS) and provide a prognosis analysis of the patients.

METHODS

A retrospective analysis of the use of the endoscopic-assisted microsurgery technique in 16 cases of large vestibular schwannoma surgery was carried out. Intraoperative nerve electrophysiological monitoring was conducted to explore the effect of neuroendoscopy on the resection of internal auditory canal tumors, protection of the facial nerve, and minimizing postoperative complications.

RESULTS

Tumors were completely removed in all 16 cases, and the facial nerve was anatomically preserved in 14 cases (87.5%). There was no postoperative cerebrospinal fluid leakage and no intracranial infection complications occurred.Following the House-Brackmann (H-B) grading system, post-operative facial nerve function was grade I in 5 cases, grade II in 6 cases, grade III in 3 cases, and grade V in 2 cases. As a result, the preservation rate of facial nerve function (H-B grade I-II) was 68.8%. All 16 patients were followed up for 3 to 24 months, and no tumor recurrence was found on enhanced MRI.

DISCUSSION

Using the endoscopic-assisted microsurgery technique in the retrosigmoid approach has many advantages over the microscopic-only approach. When compared to the microscopy-only approach, the endoscope can provide a wide-angle surgical field superior to that of a microscope in areas such as the internal auditory canal in the resection of large VS, minimize iatrogenic injuries, ensure complete removal of internal auditory canal tumors, and well as reducing postoperative complications such as cerebrospinal fluid leakage and the loss of facial and auditory nerve functions.

摘要

引言

本文旨在探讨内镜辅助显微手术技术对大型(库斯四级)前庭神经鞘瘤(VS)切除的影响,并对患者进行预后分析。

方法

对16例大型前庭神经鞘瘤手术中使用内镜辅助显微手术技术进行回顾性分析。术中进行神经电生理监测,以探讨神经内镜对切除内耳道肿瘤、保护面神经以及减少术后并发症的效果。

结果

16例患者肿瘤均完全切除,14例(87.5%)面神经获得解剖学保留。术后无脑脊液漏,未发生颅内感染并发症。按照House-Brackmann(H-B)分级系统,术后面神经功能Ⅰ级5例,Ⅱ级6例,Ⅲ级3例,Ⅴ级2例。面神经功能保留率(H-BⅠ-Ⅱ级)为68.8%。16例患者均随访3至24个月,增强MRI未发现肿瘤复发。

讨论

在乙状窦后入路中使用内镜辅助显微手术技术比单纯显微镜手术有许多优势。与单纯显微镜手术相比,在内镜辅助下切除大型VS时,在内耳道等区域,内镜可提供比显微镜更广阔的手术视野,减少医源性损伤,确保内耳道肿瘤完全切除,还能减少脑脊液漏以及面神经和听神经功能丧失等术后并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f86f/9887138/2e84b17e0475/fonc-13-1033954-g001.jpg

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