Glycologic Limited, Glasgow, G4 0BA, UK.
Glycologic Limited, Glasgow, G4 0BA, UK.
Int J Biol Macromol. 2019 Feb 1;122:572-577. doi: 10.1016/j.ijbiomac.2018.10.195. Epub 2018 Oct 31.
Within the last ten years the utilisation of dietary fibre formats (non-starch polysaccharide and resistant starch) for diarrhoea therapy, have been evaluated. These polysaccharides ferment within the colon and generate short chain fatty acids which facilitate sodium absorption. Comparisons between polysaccharide structure/physico-chemical properties and fermentation capacity in the large intestine are presented. The potential dichotomy associated with recommending dietary fibre ingestion to avoid and treat diarrhoea is also considered. Overall, this mini-review presents an overview of the current knowledge with respect to role of dietary fibre in the management (prevention and treatment) of diarrhoea (osmotic and secretory). It aims to inform the medical and non-medical communities with respect to this relatively poorly researched and understood health related area. Different forms of dietary fibre are considered in this context along with their mechanisms of action.
在过去的十年中,人们已经评估了膳食纤维形式(非淀粉多糖和抗性淀粉)在腹泻治疗中的应用。这些多糖在结肠内发酵,生成短链脂肪酸,促进钠吸收。本文介绍了多糖结构/物理化学性质和在大肠内发酵能力之间的关系。还考虑了推荐膳食纤维摄入以预防和治疗腹泻可能存在的矛盾。总的来说,本篇迷你综述概述了膳食纤维在管理(预防和治疗)腹泻(渗透性和分泌性)方面的作用的最新知识。希望向医学和非医学领域的人士介绍这个相对研究和了解较少的健康相关领域。本文还考虑了不同形式的膳食纤维及其作用机制。