Kılıçkap Mustafa, Barçın Cem, Göksülük Hüseyin, Karaaslan Doruk, Özer Necla, Kayıkçıoğlu Meral, Ural Dilek, Yılmaz Mehmet Birhan, Abacı Adnan, Arıcı Mustafa, Altun Bülent, Tokgözoğlu Lale, Şahin Mahmut
Department of Cardiology, Ankara University Faculty of Medicine, Ankara, Turkey.
Turk Kardiyol Dern Ars. 2018 Oct;46(7):525-545. doi: 10.5543/tkda.2018.15679.
Cardiovascular risc factors may show significant changes over the years. A systematic review and meta-analysis of epidemiological studies conducted in Turkey was performed to assess the latest profile and temporal changes in cardiovascular risk factors. Presented here are the data on hypertension (HT) and blood pressure (BP).
Ovid Medline, the Web of Science Core Collection, and the Turkish Academic Network and Information Center (ULAKBIM) were searched for epidemiological studies conducted in Turkey during the last 15 years. In addition, the web pages of the Ministry of Health, the Turkish Statistical Institute, and associations of cardiology, nephrology, and endocrinology were searched for appropriate studies. Regional studies were excluded. The studies included were assessed with a bias score developed by our team, then categorized as having a low risk or a high risk of bias. The crude values of HT prevalence and BP were pooled using a random effects model. Meta-regression was performed to explain heterogeneity and to assess temporal changes.
The agreement between the 2 authors on the selection and bias scoring of the studies was perfect (Kappa ≥0.95). There were 7 (n=73218) studies providing HT prevalence data, and 8 (n=75879) studies with BP data. The heterogeneity between the studies was high. Meta-analysis of the studies with a low risk of bias indicated that the crude prevalence of HT is higher in women, but that BP levels were similar in both sexes. The HT prevalence and BP value decreased between 2003 and 2012; however, the number of hypertensives stabilized at approximately 15 million, and the number of uncontrolled hypertensives, despite some decrease, was around 11 million.
Despite some improvement, HT is still an important public health problem in Turkey.
心血管危险因素可能多年来呈现显著变化。开展了一项对土耳其进行的流行病学研究的系统评价和荟萃分析，以评估心血管危险因素的最新概况和时间变化。此处呈现的是关于高血压（HT）和血压（BP）的数据。
检索了Ovid Medline、科学网核心合集以及土耳其学术网络与信息中心（ULAKBIM），查找过去15年在土耳其开展的流行病学研究。此外，还检索了卫生部、土耳其统计研究所以及心脏病学、肾脏病学和内分泌学协会的网页，查找合适的研究。排除区域研究。对纳入的研究使用我们团队制定的偏倚评分进行评估，然后分为低偏倚风险或高偏倚风险。使用随机效应模型汇总HT患病率和BP的原始值。进行Meta回归以解释异质性并评估时间变化。
两位作者在研究的选择和偏倚评分上的一致性极佳（Kappa≥0.95）。有7项研究（n = 73218）提供了HT患病率数据，8项研究（n = 75879）提供了BP数据。研究之间的异质性较高。对低偏倚风险研究的荟萃分析表明，HT的原始患病率在女性中较高，但两性的BP水平相似。2003年至2012年期间，HT患病率和BP值有所下降；然而，高血压患者人数稳定在约1500万左右，尽管有所下降，但未得到控制的高血压患者人数仍约为1100万。
尽管有所改善，但HT在土耳其仍是一个重要的公共卫生问题。
