Department of Public Health, Faculty of Medicine, Izmir Katip Celebi University, Izmir 35620, Türkiye.
Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Medicina (Kaunas). 2023 Jul 26;59(8):1366. doi: 10.3390/medicina59081366.
: An important Non-Communicable Disease risk factor, hypertension (HT), is highly prevalent and controlled HT rates are not sufficient which increases the risk of developing premature deaths. The purpose of the study is to evaluate differences in all-cause and cardiovascular-related mortality according to HT status by using national data from Chronic Diseases and Risk Factors Survey in Turkey (2011-2017). Cox regression models were used to estimate hazard ratios (HR) for predicting the all-cause and cardiovascular system-related mortalities. Median follow-up period was 6.2 years. Among individuals with HT, 41.8% was untreated, 30.1% received treatment and had controlled blood pressure, and 28.1% were under treatment but had uncontrolled BP levels. The hazard for mortality among treated & uncontrolled hypertensive participants was significantly higher for all-cause (HR = 1.32, 95% CI = 1.06-1.65), cardiovascular (HR = 2.11, 95% CI = 1.46-3.06), heart disease (HR = 2.24, 95% CI = 1.46-3.43), and Coronary Heart Disease mortality (HR = 2.66, 95% CI = 1.56-4.53) compared to normotensive participants. Individuals with HT who were treated but do not have controlled blood pressure in Turkey had a significantly increased risk of Cardiovascular Disease and all-cause mortality. Along with studies investigating the causes of uncontrolled blood pressure despite initiation of treatment, support should be provided to patients in cases of non-adherence to antihypertensive medication or life change recommendations.
高血压是一种重要的非传染性疾病危险因素，其患病率很高，而控制率却不足，这增加了发展为过早死亡的风险。本研究旨在使用土耳其慢性疾病和危险因素调查（2011-2017 年）的全国数据，评估根据高血压状态的全因和心血管相关死亡率的差异。Cox 回归模型用于估计预测全因和心血管系统相关死亡率的风险比（HR）。中位随访期为 6.2 年。在高血压患者中，41.8%未接受治疗，30.1%接受治疗且血压得到控制，28.1%接受治疗但血压控制不佳。治疗但血压控制不佳的高血压患者的全因（HR=1.32，95%CI=1.06-1.65）、心血管（HR=2.11，95%CI=1.46-3.06）、心脏病（HR=2.24，95%CI=1.46-3.43）和冠心病死亡率（HR=2.66，95%CI=1.56-4.53）的死亡风险明显高于血压正常的参与者。土耳其接受治疗但血压未得到控制的高血压患者发生心血管疾病和全因死亡的风险显著增加。除了研究治疗开始后血压控制不佳的原因外，还应针对不遵守抗高血压药物或生活方式改变建议的患者提供支持。
