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退行性椎间盘疾病后路短节段融合术后矢状位平衡评估。

Sagittal alignment assessment after short-segment lumbar fusion for degenerative disc disease.

机构信息

Spine Center Stuttgart, Paulinenhilfe, Diakonie-Klinikum Stuttgart, Stuttgart, Germany.

First Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

Int Orthop. 2019 Apr;43(4):891-898. doi: 10.1007/s00264-018-4222-2. Epub 2018 Nov 4.

Abstract

PURPOSE

To investigate whether differences in spinopelvic parameters, and especially spinopelvic alignment, could be associated with adjacent segment disease (ASD) or pseudarthrosis after short-segment lumbar fusion.

METHODS

Retrospective study of patients offered mono- or bisegmental transforaminal lumbar interbody fusion (TLIF) with polyetheretherketone (PEEK) or titanium cages, due to degenerative disease. Of 419 patients, 32 (7.6%) presented pseudarthrosis (nonunion group), 29 (6.9%) developed symptomatic ASD (ASD group), and 358 patients (85.5%) showed evidence of uncomplicated fusion (control group). Standard spinopelvic parameters were measured in all patients before and after surgery. The differences of the values within the parameters (Δ values) were also calculated. A comparative analysis within and among groups was performed. Patients were also analyzed by cage characteristics (large vs small, titanium vs PEEK).

RESULTS

All studied parameters changed significantly after surgery both in the control and ASD group, while in the nonunion group, only LL and PI-LL changed significantly (PI-LL increased from 10 ± 11° to 14 ± 10°, p = 0.008). Patients in the nonunion group presented greater SS before and after surgery, greater PI-LL after surgery, and higher PI, while ASD patients presented greater absolute mean ΔPT value. Age, size, and type of cage were not related to fusion, nonunion, or ASD.

CONCLUSIONS

Greater SS, greater PI, and a PI-LL mismatch greater than 10° are associated with failed bony fusion, while ASD is related to a greater difference between the pre-operative and post-operative values of PT. Neither the type nor the size of cage seem to have a significant impact on either solid bony fusion, nonunion, or ASD rates. Thus, we recommend on the study of patients' sagittal alignment in the pre-operative setting even when treating patients with short-segment lumbar interbody fusion.

摘要

目的

研究脊柱骨盆参数,特别是脊柱骨盆对线的差异是否与短节段腰椎融合术后的邻近节段疾病(ASD)或假关节有关。

方法

回顾性研究因退行性疾病接受单节段或双节段经椎间孔腰椎体间融合术(TLIF)的患者,使用聚醚醚酮(PEEK)或钛笼。419 例患者中,32 例(7.6%)出现假关节(非融合组),29 例(6.9%)出现症状性 ASD(ASD 组),358 例(85.5%)显示无并发症融合证据(对照组)。所有患者术前和术后均测量标准脊柱骨盆参数,并计算参数内的差值(Δ 值)。对组内和组间进行对比分析。还根据笼的特征(大 vs 小、钛 vs PEEK)对患者进行分析。

结果

对照组和 ASD 组所有研究参数在术后均显著改变,而非融合组仅 LL 和 PI-LL 显著改变(PI-LL 从 10°±11°增加到 14°±10°,p=0.008)。非融合组术前和术后 SS 更大,术后 PI-LL 更大,PI 更高,而 ASD 患者的绝对平均 ΔPT 值更大。年龄、笼的大小和类型与融合、不融合或 ASD 无关。

结论

更大的 SS、更大的 PI 和 PI-LL 差值大于 10°与骨融合失败相关,而 ASD 与 PT 术前和术后值之间的差异更大相关。笼的类型和大小似乎对骨融合、不融合或 ASD 的发生率均无显著影响。因此,我们建议即使在进行短节段腰椎体间融合术的患者中,也应在术前研究患者的矢状面排列。

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