Department of Urology, Hacettepe University School of Medicine, Ankara, Turkey.
Department of Urology, Hacettepe University School of Medicine, Ankara, Turkey.
J Pediatr Urol. 2019 Feb;15(1):67.e1-67.e6. doi: 10.1016/j.jpurol.2018.09.019. Epub 2018 Oct 10.
Nomograms and scoring systems designed for predicting the success of percutaneous nephrolithotomy (PCNL) in adults are currently available. However, no scoring system currently exists primarily for predicting PCNL success in children.
The objective of this study was to develop a scoring system to predict the stone-free and complication rates by using pre-operative parameters.
A retrospective analysis was conducted on data from 434 renal units belonging to patients with kidney stones who underwent PCNL between 1997 and 2017. Renal stone index was calculated by dividing the length of the stone along its longest axis by the length of the kidney along its longest axis. Guy's Stone scores, S.T.O.N.E scores, and CROES scores for adults were calculated by filling in the variables for each patient. Factors that predicted success and complications were examined by univariate and multivariate analyses.
Mean age was 8.3 (1-16) years, and male to female ratio was 236:165. When stone-free patients were compared with other patients, there was a statistically significant difference in the average stone/kidney index (SKI) value (stone size/kidney size on longitudinal axis) (0.266 vs 0.339, P < 0.001). In multivariate analysis, factors that predicted success were the SKI and number of stones. A newly developed scoring scale, the stone-kidney score (SKS), combined scores for both the SKI and the number of stones into one value. A minimum total SKS score was 2, and a maximum total SKS score was 4. Success rates for SKS scores of 2, 3, and 4 were 86.4%, 73%, and 62.9% (P < 0.001), respectively. Complication rates for SKS scores of 2, 3, and 4 were 13%, 22.1%, and 23.8%, respectively.
The new scoring system has only two variables (number of stones and SKI) and three risk groups. An SKS score is easier to use and calculate. An SKI value can be simply calculated on any imaging modality by dividing the length of the stone along its longest axis by the length of the kidney along its longest axis. As in the new scoring system, the SKI value combined with the number of stones is useful in predicting stone-free rates after PCNL.
When evaluated together, the SKI and presence of multiple stones may predict stone-free rates pre-operatively. The SKS is an individual-specific method that can be easily used in pediatric clinical practice. Further studies are required to develop and standardize this method.
目前已有用于预测经皮肾镜碎石取石术(PCNL)成人成功率的列线图和评分系统。然而,目前尚无主要用于预测儿童 PCNL 成功率的评分系统。
本研究旨在开发一种评分系统,通过使用术前参数预测结石清除率和并发症发生率。
回顾性分析了 1997 年至 2017 年间接受 PCNL 的 434 个肾结石患者的肾脏单位数据。通过沿最长轴测量结石的长度与肾脏的长度之比计算肾结石指数(renal stone index)。根据每位患者的变量计算成人的 Guy's Stone 评分、S.T.O.N.E 评分和 CROES 评分。通过单变量和多变量分析检查预测成功和并发症的因素。
平均年龄为 8.3(1-16)岁,男女比例为 236:165。与非结石清除患者相比,结石/肾脏指数(SKI)平均值(沿纵轴的结石大小/肾脏大小)有统计学意义(0.266 与 0.339,P<0.001)。多变量分析表明,成功的预测因素是 SKI 和结石数量。新开发的评分量表——结石-肾脏评分(SKS)将 SKI 和结石数量的评分合并为一个值。SKS 的最低总分为 2,最高总分为 4。SKS 评分为 2、3 和 4 的成功率分别为 86.4%、73%和 62.9%(P<0.001)。SKS 评分为 2、3 和 4 的并发症发生率分别为 13%、22.1%和 23.8%。
新的评分系统只有两个变量(结石数量和 SKI)和三个风险组。SKS 评分更容易使用和计算。SKI 值可以通过沿最长轴测量结石的长度与沿最长轴测量肾脏的长度之比,在任何成像方式上简单计算。正如在新的评分系统中一样,SKI 值结合结石数量可用于预测 PCNL 后结石清除率。
SKI 值和多发性结石的存在可共同预测术前结石清除率。SKS 是一种个体特异性方法,可在儿科临床实践中轻松使用。需要进一步的研究来开发和规范这种方法。