Altunkol Adem, Alma Ergün, Anıl Hakan, Özbilen Mert Hamza, Aksay Buğra, Deniz Mehmet Eflatun
Department of Urology, University of Health Sciences, Adana City Teaching and Research Hospital, Adana, Turkey.
Faculty of Medicine, Department of Urology, İstanbul Aydın University, Istanbul, Turkey.
Urolithiasis. 2025 May 14;53(1):90. doi: 10.1007/s00240-025-01762-9.
Kidney stone disease is relatively uncommon in pediatric populations, although its incidence has been steadily increasing in endemic regions. Mini-percutaneous nephrolithotomy (mini-PCNL), considered the most suitable approach for the treatment of large kidney stones, offers a minimally invasive option with fewer complications. This study evaluates the predictive accuracy of the STONE, Guy's Stone Score, and stone-kidney size (SKS) scoring systems in determining stone-free rates following pediatric mini-PCNL procedures. In this retrospective analysis, data were reviewed from 79 individuals younger than 18 who received mini-PCNL treatment from January 2021 to June 2024. Patients were evaluated as residual group and stone-free group. The diagnostic performance of the nomograms in detecting residual stones was evaluated using ROC analysis, and predictive factors for stone-free success were identified through logistic regression modeling. Guy's score (cut-off 1.5) had 79.3% sensitivity, 70% specificity, and AUC 0.817. The STONE score (cut-off 5.5) showed 69% sensitivity, 68% specificity, and AUC 0.741. SKS score (cut-off 3.5) resulted in 62.1% sensitivity, 78% specificity, and AUC 0.768. Logistic regression found stone size (OR: 1.137, p < 0.001) and volume (OR: 1.001, p < 0.001) were linked to stone-free success. Guy's score (OR: 5.438, p < 0.001), STONE score (OR: 1.741, p < 0.001), and SKS (OR: 3.972, p < 0.001) were strong predictors, but in multivariate analysis, only Guy's score (OR: 3.701, p = 0.010) remained significant. The results of our study demonstrate that the Guy's stone score is the most reliable prognostic tool for predicting stone-free success in pediatric patients undergoing mini-PCNL. Moreover, variables such as stone size and volume exert a substantial influence on the surgical outcomes.
肾结石病在儿科人群中相对不常见,尽管其发病率在流行地区一直在稳步上升。迷你经皮肾镜取石术(mini-PCNL)被认为是治疗大肾结石最合适的方法,它提供了一种微创选择,并发症较少。本研究评估了STONE、盖伊结石评分和结石-肾脏大小(SKS)评分系统在确定小儿mini-PCNL术后无结石率方面的预测准确性。在这项回顾性分析中,我们回顾了2021年1月至2024年6月期间接受mini-PCNL治疗的79名18岁以下患者的数据。将患者分为残留组和无结石组。使用ROC分析评估列线图检测残留结石的诊断性能,并通过逻辑回归模型确定无结石成功的预测因素。盖伊评分(临界值1.5)的灵敏度为79.3%,特异度为70%,AUC为0.817。STONE评分(临界值5.5)的灵敏度为69%,特异度为68%,AUC为0.741。SKS评分(临界值3.5)的灵敏度为62.1%,特异度为78%,AUC为0.768。逻辑回归发现结石大小(OR:1.137,p < 0.001)和体积(OR:1.001,p < 0.001)与无结石成功相关。盖伊评分(OR:5.438,p < 0.001)、STONE评分(OR:1.741,p < 0.001)和SKS(OR:3.972,p < 0.001)是强有力的预测因素,但在多变量分析中,只有盖伊评分(OR:3.701,p = 0.010)仍然显著。我们的研究结果表明,盖伊结石评分是预测接受mini-PCNL的小儿患者无结石成功的最可靠预后工具。此外,结石大小和体积等变量对手术结果有重大影响。