Epidemiology Consult Service, U.S. Air Force School of Aerospace Medicine, 2510 Fifth Street, Bldg 840, Rm W318.23, Wright-Patterson Air Force Base, OH 45433, USA.
559th Medical Group, Wilford Hall Ambulatory Surgical Center, 1440 McGuire Street, Bldg 7206, Joint Base San Antonio-Lackland, TX 78235, USA.
Prev Med. 2019 Jan;118:142-149. doi: 10.1016/j.ypmed.2018.10.023. Epub 2018 Oct 26.
Chemoprophylaxis with intramuscular benzathine penicillin G has been used widely by the U.S. military to prevent epidemics of group A streptococcus infections during basic training. The recent global shortage of benzathine penicillin prompted a detailed analysis of this issue in 2017 by military preventive medicine and infectious disease authorities in San Antonio, Texas, and San Diego, California, USA. This paper explores the history of group A streptococcus and chemoprophylaxis in the U.S. military training environment, current policy and practice, and challenges associated with widespread chemoprophylaxis. In light of the history presented, preventive medicine authorities at basic training centers should be extremely cautious about discontinuing benzathine penicillin chemoprophylaxis.
肌肉注射苄星青霉素 G 进行化学预防已被美国军方广泛用于预防基本训练期间 A 组链球菌感染的流行。最近全球苄星青霉素短缺促使美国德克萨斯州圣安东尼奥和加利福尼亚州圣地亚哥的军事预防医学和传染病当局在 2017 年对此问题进行了详细分析。本文探讨了 A 组链球菌和美国军事训练环境中的化学预防史、当前政策和实践以及广泛化学预防相关的挑战。有鉴于此，基础训练中心的预防医学当局应极其谨慎地停止使用苄星青霉素化学预防。
