Department of Cardiothoracic Anesthesia, Mohammed Bin Khalifa Bin Salman Al Khalifa Cardiac Center, Royal Medical Services, Awali, Bahrain.
Evidence Anesthesia Review Group (EAR), Department of Pharmacology, Faculty of Medicine of Complutense University of Madrid, Madrid, Spain.
Minerva Anestesiol. 2019 Feb;85(2):173-188. doi: 10.23736/S0375-9393.18.13170-1. Epub 2018 Oct 30.
Brugada Syndrome is characterized by arrhythmogenic risk that may be exacerbated by different metabolic and pharmacological factors. Since its first description, knowledge of this syndrome and its detection by physicians belonging to different specialties have gradually increased. The risk of arrhythmias is well known to increase in the postoperative period, and this risk is particularly accentuated in patients with Brugada Syndrome. The purpose of this review is to analyze the relationship between this syndrome and anesthesia; establish recommendations for the safe management of these patients in the surgical setting; and update the relevant concepts regarding the safety of drug administration in individuals with Brugada Syndrome.
Brugada 综合征的特征是心律失常风险，不同的代谢和药理因素可能会使其恶化。自首次描述以来，不同专业医生对该综合征的认识及其检测能力逐渐提高。众所周知，心律失常风险在术后期间会增加，而 Brugada 综合征患者的这种风险更为突出。本综述的目的是分析该综合征与麻醉之间的关系；为这些患者在手术环境中的安全管理制定建议；并更新有关 Brugada 综合征患者药物管理安全性的相关概念。
