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牙周炎发病和进展预测模型:系统评价。

Prediction models for the incidence and progression of periodontitis: A systematic review.

机构信息

Australian Research Centre for Population Oral Health, the University of Adelaide, Adelaide, South Australia, Australia.

Central Laboratory, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.

出版信息

J Clin Periodontol. 2018 Dec;45(12):1408-1420. doi: 10.1111/jcpe.13037. Epub 2018 Nov 25.

Abstract

AIMS

To comprehensively review, identify and critically assess the performance of models predicting the incidence and progression of periodontitis.

METHODS

Electronic searches of the MEDLINE via PubMed, EMBASE, DOSS, Web of Science, Scopus and ProQuest databases, and hand searching of reference lists and citations were conducted. No date or language restrictions were used. The Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modelling Studies checklist was followed when extracting data and appraising the selected studies.

RESULTS

Of the 2,560 records, five studies with 12 prediction models and three risk assessment studies were included. The prediction models showed great heterogeneity precluding meta-analysis. Eight criteria were identified for periodontitis incidence and progression. Four models from one study examined the incidence, while others assessed progression. Age, smoking and diabetes status were common predictors used in modelling. Only two studies reported external validation. Predictive performance of the models (discrimination and calibration) was unable to be fully assessed or compared quantitatively. Nevertheless, most models had "good" ability to discriminate between people at risk for periodontitis.

CONCLUSIONS

Existing predictive modelling approaches were identified. However, no studies followed the recommended methodology, and almost all models were characterized by a generally poor level of reporting.

摘要

目的

全面回顾、识别和批判性评估预测牙周炎发病和进展的模型的性能。

方法

通过 PubMed 的 MEDLINE、EMBASE、DOSS、Web of Science、Scopus 和 ProQuest 数据库进行电子搜索,并手动搜索参考文献和引文。未对检索时间和语言进行限制。在提取数据和评估所选研究时,遵循了预测模型研究的系统评价的批判性评价和数据提取清单。

结果

在 2560 条记录中,纳入了五项研究(共 12 个预测模型)和三项风险评估研究。预测模型存在很大的异质性,不适合进行荟萃分析。确定了 8 个牙周炎发病和进展的标准。有一个研究中的四个模型检验了发病情况,而其他模型则评估了进展情况。年龄、吸烟和糖尿病状况是建模中常用的预测因素。只有两项研究报告了外部验证。模型的预测性能(区分度和校准度)无法进行全面评估或定量比较。然而,大多数模型在区分牙周炎高危人群方面具有“良好”的能力。

结论

确定了现有的预测建模方法。然而,没有研究遵循推荐的方法学,并且几乎所有模型的报告水平普遍较差。

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